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Length of the chromosomal segment marked by galactose-1-phosphate uridyl transferase and soluble aconitase and conserved since divergence of lineages leading to mouse and man

Published online by Cambridge University Press:  14 April 2009

Joseph H. Nadeau
Joseph H. Nadeau
Affiliation:
The Jackson Laboratory, Bar Harbor, Maine 04609
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Standard linkage testing crosses and ovarian teratoma mapping were used to estimate the length of the chromosomal segment that is marked by galactose-1-phosphate uridyl transferase and soluble aconitase and that has been conserved since divergence of lineages leading to mouse and man. These experiments were also used to determine whether the Rb(4·6)2Bnr Robertsonian translocation suppresses recombination on the proximal portion of mouse Chromosome 4. The estimated length of the conserved segment marked by galactose-1-phosphate uridyl transferase and soluble aconitase in mouse and man was estimated to be 24 cM. It was also shown that Rb(4·6)2Bnr strongly suppressed recombination on the centromeric portion of mouse Chromosome 4.

Type
Research Article
Information
Genetics Research , Volume 52 , Issue 2 , October 1988 , pp. 141 - 144
Copyright
Copyright © Cambridge University Press 1988

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