Hostname: page-component-586b7cd67f-tf8b9 Total loading time: 0 Render date: 2024-11-28T01:23:46.012Z Has data issue: false hasContentIssue false

Induction of lethal mutations in Drosophila melanogaster by DNA

Published online by Cambridge University Press:  14 April 2009

S. Gershenson
Affiliation:
Institute of Zoology, Academy of Sciences of the Ukrainian S.S.R., Kiev, U.S.S.R.
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Addition to the food of Drosophila larvae of DNA from calf thymus induces a considerable number of recessive lethal mutations in the 2nd chromosome. An analysis of sixty-six such lethals showed that most of them affect the same segment containing probably some thirty to thirty-five sub-units capable of mutating together or separately.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1965

References

REFERENCES

Auerbach, C. (1946). Chemically induced mosaicism in Drosophila melanogaster. Proc. R. Soc. Edinb. B, 62, 211221.Google ScholarPubMed
Auerbach, C. (1950). Possible differences between the effects of chemical and physical mutagens. Pubbl. Staz. zool. Napoli, 12 (Suppl.), 121.Google Scholar
Fahmy, O. G. & Fahmy, M. J. (1961). Induction of mutations by deoxyribonucleic acid in Drosophila melanogaster. Nature, Lond. 191, 776779.CrossRefGoogle ScholarPubMed
Fahmy, O. G. & Fahmy, M. J. (1962). Mutagenic activity of cellular macromolecules in Drosophila melanogaster. Nature, Lond. 196, 873876.CrossRefGoogle Scholar
Gershenson, S. (1939). Induction of directed mutations in Drosophila. Dokl. Akad. Nauk SSSR, 25, 224227.Google Scholar
Gershenson, S. (1940). Character of mutations induced by thymonucleic acid in Drosophila. Dokl. Akad. Nauk SSSR, 26, 609611.Google Scholar
Gershenson, S., Zilberman, R. A., Liovochkina, O. A., Sytko, P. O. & Tarnavsky, N. D. (1948). Induction of mutations in Drosophila by thymonucleic acid. Zh. obshch. Biol. 9, 6988.Google Scholar
Gershenson, S. & Kisseliova, I. A. (1958). Induction of hereditary changes in Drosophila melanogaster. Dokl. Akad. Nauk SSSR, 123, 554557.Google Scholar
Kisseliova-Fedorenko, I. A. & Miloserdova, V. D. (1963). On the induction of directed mutations in insects. In Materials on the Entomology of Ukraine, pp. 7584. Kiev: Acad. Sci. Ukrainian S.S.R.Google Scholar
Mathew, C. (1964). The nature of delayed mutations after treatment with chloroethyl methanesulphonate and other alkylating agents. Mutat. Res. 1, 163172.CrossRefGoogle Scholar
Shkurba, V. V. (1963). On a class of decoding problems. In: Seminar on Mathematical Methods in Biology and Bionics, pp. 1334. Kiev: Acad. Sci. Ukrainian S.S.R.Google Scholar