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Induction of cytoplasmic respiratory deficiency in yeast by phenethyl alcohol

Published online by Cambridge University Press:  14 April 2009

D. Wilkie
Affiliation:
Department of Botany, University College London
N. G. Maroudas
Affiliation:
Department of Botany, University College London
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Phenethyl alcohol is shown to induce cytoplasmic respiratory deficiency (petite mutation) in various strains of Saccharomyces cerevisiae. Apart from petite induction, phenethyl alcohol also affects cell growth both in respiratile and non-respirable media. This sensitivity to growth inhibition appears to be complex, and does not correlate with the degree of induction of respiratory deficiency.

Type
Short Papers
Copyright
Copyright © Cambridge University Press 1969

References

REFERENCES

Hawthorne, D. C. & Mortimer, R. (1960). Chromosome mapping in Saccharomyces: centromere-linked genes. Genetics 45, 10851110.CrossRefGoogle ScholarPubMed
Jacob, F., Brenner, S. & Cuzin, F. (1963). On the regulation of DNA replication in bacteria. Cold Spring Harb. Symp. Quant. Biol. 28, 329347.CrossRefGoogle Scholar
Lark, D. C. & Lark, C. (1966). Regulation of chromosome replication in Escherichia coli: a comparison of the effects of phenethyl alcohol treatment with those of amino acid starvation. J. molec. Biol. 20, 919.CrossRefGoogle ScholarPubMed
Marchant, R. & Smith, D. G. (1968). Membranous structures in yeast. Biol. Rev. 43, 459480.CrossRefGoogle Scholar
Mounolou, J. C., Jakob, H. & Slonimski, P. P. (1967). Molecular nature of hereditary cytoplasmic factors controlling gene expression in mitochondria. In Goldstein, L. (ed.), The Control of Nuclear Activity. New Jersey: Prentice-Hall.Google Scholar
Roodyn, D. B. & Wilkie, D. (1968). The Biogenesis of Mitochondria. London: Methuen.Google Scholar
Rosenkranz, H. S., Mednis, A., Marks, P. A. & Rose, H. M. (1967). Metabolie effects of phenethyl alcohol on mammalian cells. Biochem. Biophys. Acta 149, 513518.Google Scholar
Smith, D. G., Marchant, R., Maroudas, N. G. & Wilkie, D. (1968). Comparative study of the ultrastructure of petite strains of Saccharomyces cerevisiae. J. gen Microbiol. (in the Press).Google Scholar
Terenzi, H. F. & Storce, R. (1968). Stimulation by phenethyl alcohol of aerobic fermentation in Mucor rouxii. Biochem. biophys. Res. Commun. 30, 447452.CrossRefGoogle ScholarPubMed
Treick, R. W. and Konetzka, W. A. (1964). Physiological state of Escherichia coli and the inhibition of DNA synthesis by phenethyl alcohol. J. Boot. 88, 15801584.Google ScholarPubMed