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Immunogenetics of an antigen identified in both sheep and cattle sera

Published online by Cambridge University Press:  14 April 2009

Giovanna De Benedictis ,
P. Capalbo  and
E. Gallina
Giovanna De Benedictis
Affiliation:
Department of Cellular Biology, University of Calabria, Arcavacata (CS), Italy
P. Capalbo
Affiliation:
Department of Cellular Biology, University of Calabria, Arcavacata (CS), Italy
E. Gallina
Affiliation:
Department of Cellular Biology, University of Calabria, Arcavacata (CS), Italy
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Summary

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Alloimmunization in sheep revealed an antigen specificity B1 which is also to be found in cattle sera. The molecular weight of the protein carrying B1 was greater in sheep than in cattle, whilst in both cases its isoelectric point was at pH 6·2. The electrophoretic position of the antigen suggests that the molecule carrying B1 might be a β-globulin. Family studies indicated that in both species B1 was inherited in a simple Mendelian manner, as if it were a product of a dominant allele B1 at an autosomal locus B.

Type
Research Article
Information
Genetics Research , Volume 34 , Issue 1 , August 1979 , pp. 41 - 46
Copyright
Copyright © Cambridge University Press 1979

References

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