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Heterosis among lines of mice selected for body weight: 3. Thermoregulation

Published online by Cambridge University Press:  14 April 2009

Carol Becker Lynch ,
R. C. Roberts  and
W. G. Hill
Carol Becker Lynch
Affiliation:
Department of Biology, Wesleyan University, Middletown, CT 06457
R. C. Roberts
Affiliation:
Institute of Animal Genetics, University of Edinburgh, West Mains Road, Edinburgh EH9 3JN
W. G. Hill
Affiliation:
Institute of Animal Genetics, University of Edinburgh, West Mains Road, Edinburgh EH9 3JN
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Crosses were made among 18 lines of mice, six previously selected for large 6-week weight, six for small 6-week weight, and six unselected controls, comprising a complete diallel cross among sizes and a partial diallel cross among replicate lines within sizes, and all purebred matings. Across all groups large size was associated with lower weight-specific food consumption and brown adipose tissue, and increased nest-building. Overall the crosses had lower weight-specific food consumption, and increased nest-building, body temperature, and brown adipose tissue than the purebreds. In general, heterosis in crosses between lines of different size, especially those involving large lines, tended to exceed that in crosses between lines of the same size.

Type
Research Article
Information
Genetics Research , Volume 48 , Issue 2 , October 1986 , pp. 95 - 100
Copyright
Copyright © Cambridge University Press 1986

References

Bhuvanakumar, C. K., Lynch, C. B., Roberts, R. C. & Hill, W. G. (1985). Heterosis among lines of mice selected for body weight. 1. Growth. Theoretical and Applied Genetics 71, 44–51.Google Scholar
Connolly, M. S. & Lynch, C. B. (1983). Classical genetic analysis of circadian body temperature rhythms in mice. Behavioral Genetics 13, 491–500.Google Scholar
Falconer, D. S. (1973). Replicated selection for body weight in mice. Genetical Research 22, 291–321.CrossRefGoogle ScholarPubMed
Falconer, D. S. (1981). Introduction to quantitative genetics. New York: Longman, Inc.Google Scholar
Harvey, W. R. (1977). Users guide for LSML76. Mixed model least-squares and maximum likelihood computer program. Ohio State University, Columbus.Google Scholar
Heldmaier, G. & Buchberger, A. (1985). Sources of heat during nonshivering thermogenesis in Djungarian hamsters: a dominant role of brown adipose tissue during cold adaptation. Journal of Comparative Physiology 156, 237–245.Google Scholar
Lacy, R. C. & Lynch, C. B. (1979). Quantitative genetic analysis of temperature regulation in Mus musculus. I. Partitioning of variance. Genetics 91, 743–753.Google Scholar
Lynch, C. B. & Roberts, R. C. (1984). Aspects of temperature regulation in mice selected for large and small size. Genetical Research 43, 299–306.Google Scholar
Lynch, C. B. & Sulzbach, D. S. (1984). Quantitative genetic analysis of temperature regulation in Mus musculus. II. Diallel analysis of individual traits. Evolution 38, 527–540.Google Scholar
Robertson, A. (1955). Selection in animals: synthesis. Cold Spring Harbor Symposium on Quantitative Biology 20, 225–229.CrossRefGoogle ScholarPubMed
Sulzbach, D. S. & Lynch, C. B. (1984). Quantitative genetic analysis of temperature regulation in Mus musculus. III. Diallel analysis of correlations between traits. Evolution 38, 541–552.Google ScholarPubMed