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‘Grizzled’, a mutant in linkage group X of the mouse

Published online by Cambridge University Press:  14 April 2009

Joyce L. Bloom  and
D. S. Falconer
Joyce L. Bloom
Affiliation:
Institute of Animal Genetics, Edinburgh
D. S. Falconer
Affiliation:
Institute of Animal Genetics, Edinburgh
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Grizzled (gr) is a recessive gene with complete penetrance but reduced viability. It is linked with waltzer (v) in linkage group X, the recombination frequency being 14·6 ± 2·6%. Its visible effect is to dilute the yellow pigment of the hairs. Body weight is reduced by about 25% atbirth and remains at about 10–20% below that of non-grizzled litter mates. Viability up to the time of classification is about 50–60% of that of non-grizzled litter mates. The mortality of grizzled homo-zygotes occurs at all stages from about 10 days of gestation up to the time of classification. No specific cause of the mortality was evident.

Type
Research Article
Information
Genetics Research , Volume 7 , Issue 2 , April 1966 , pp. 159 - 167
Copyright
Copyright © Cambridge University Press 1966

References

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