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The genetics of Sleek: a possible regulatory mutation of the tabby-crinkled-downless syndrome

Published online by Cambridge University Press:  14 April 2009

Mark Crocker  and
Bruce M. Cattanach
Mark Crocker
Affiliation:
MRC Radiobiology Unit, Harwell, Oxon.
Bruce M. Cattanach
Affiliation:
MRC Radiobiology Unit, Harwell, Oxon.
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Summary

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A new mutation, Sleek, similar in appearance to mutations at the Ta, cr and dl loci, has been investigated. It is inherited as an autosomal dominant and maps very close to dl on chromosome 13. Allelism with dl seems probable since Sleek interacts with dl but not with cr. The unusual occurrence of dominant and recessive alleles at the same locus which produce a similar mutant phenotype suggests that the locus might either code for a multimeric protein or a regulatory product.

Type
Research Article
Information
Genetics Research , Volume 34 , Issue 3 , December 1979 , pp. 231 - 238
Copyright
Copyright © Cambridge University Press 1979

References

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