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Genetics of host-controlled restriction and modification in Escherichia coli

Published online by Cambridge University Press:  14 April 2009

S. W. Glover  and
C. Colson
S. W. Glover
Affiliation:
Medical Research Council, Microbial Genetics Research Unit, Department of Molecular Biology, King's Buildings, West Mains Road, Edinburgh 9
C. Colson
Affiliation:
Institut Carnoy, University of Louvain, 24 Rue du Canal, Louvain, Belgium
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The sites of mutations affecting host-controlled modification (HCM) have been mapped in E. coli K and E. coli B by conjugation and transduction experiments between mutants. These mutations all map close to the serB locus on the opposite side to the marker thr. Non-parental HCM has been observed among colonies obtained from Pl transduction experiments between HCM mutants. Control experiments have shown that these non-parental recombinants can not be accounted for by reversion of either parent and must result from recombination between mutants. Several genetic models are suggested which could account for these recombinants and an attempt is made to distinguish between various models by testing for complementation between mutants in a zygotic induction complementation test.

Type
Research Article
Information
Genetics Research , Volume 13 , Issue 2 , April 1969 , pp. 227 - 240
Copyright
Copyright © Cambridge University Press 1969

References

REFERENCES

Adams, H. M. (1950). Methods for the study of bacterial viruses. Meth. med. Res. 2, 1–73.Google Scholar
Appleyard, R. K. (1954). Segregation of new lysogenic types during growth of doubly lysogenic strain derived from Escherichia coli K-12. Genetica 39, 440–452.CrossRefGoogle Scholar
Arber, W. (1958). Transduction des caractéres gal par le bacteriophage λ. Archs. Sci., Genéve 11, 259–330.Google Scholar
Arber, W. (1960). Polylysogeny for bacteriophage lambda. Virology 11, 250–272.CrossRefGoogle Scholar
Arber, W. (1965 a). Host-controlled modification of bacteriophage. A. Rev. Microbiol. 19, 365–378.CrossRefGoogle ScholarPubMed
Arber, W. (1965 b). Host specoficity of DNA produced by Escherichia coli. V. The role of methionine in the production of host specificity. J. molec. Biol. 11, 247–256.CrossRefGoogle ScholarPubMed
Arber, W. & Dussoix, D. (1962). Host specificity of DNA produced by Escherichia coli. I. Host controlled modification of bacteriophage λ. J. molec. Biol. 5, 18–36.CrossRefGoogle ScholarPubMed
Arber, W. & Smith, J. D. (1966). Host controlled modification of phage and its correlation with specific methylation of desoxyribonucleotides. IXth Int. Congr. Microbiol. p. 5.Google Scholar
Bertani, G. & Weigle, J. J. (1953). Host-controlled variation in bacterial viruses. J. Bact. 65, 113–121.CrossRefGoogle ScholarPubMed
Boyer, H. (1964). Genetic control of restriction and modification in Escherichia coli. J. Bact. 88, 1652–1660.CrossRefGoogle ScholarPubMed
Cohen, G. & Jacob, P. (1959). Sur la répression de la synthese des enzymes intervenant dans la formation du tryptophane chez Escherichia coli. C. r. hebd. Séanc. Acad. Sci., Paris 248, 3490.Google Scholar
Colson, C., Glover, S. W., Symonds, N. D. & Stacey, K. A. (1965). The location of the genes for host-controlled modification and restriction in Escherichia coli K-12. Genetics 52, 1043–1050.CrossRefGoogle ScholarPubMed
Dussoix, D. & Arber, W. (1962). Host specificity of DNA produced by Escherichia coli. II. Control over acceptance of DNA from infecting phage. J. molec. Biol. 5, 37–49.CrossRefGoogle ScholarPubMed
Glover, S. W. (1962). Valine resistant mutants of Escherichia coli K-12. Genet. Res. 3 448–460.CrossRefGoogle Scholar
Glover, S. W. (1968). Host specificity in F' heterogenotes of Escherichia coli. J. gen. Microbiol. 53, i–ii.Google ScholarPubMed
Glover, S. W. & Colson, C. (1965). The breakdown of the restriction mechanism in zygotes of Escherichia coli. Genet. Res. 6, 153–155.CrossRefGoogle ScholarPubMed
Glover, S. W., Schell, J., Symonds, N. D. & Stacey, K. A. (1963). The control of host-induced modification by phage P 1. Genet. Res. 4, 480–482.CrossRefGoogle Scholar
Hayes, W. (1953). The mechanism of genetic recombination in Escherichia coli. Cold Spring Harb. Symp. quant. Biol. 18, 75–93.CrossRefGoogle ScholarPubMed
Hoekstra, W. P. M. & De Haan, P. G. (1965). The location of the restriction locus for λK in Escherichia coli B. Mutation Res. 2, 204–212.CrossRefGoogle Scholar
Jacob, F. & Wollman, E. L. (1954). Etude genetique d'un bacteriophage tempere d'Escherichia coli. I. Le system genetique du bacteriophage λ. Annls. Inst. Pasteur, Paris 87, 654–673.Google Scholar
Klein, A. (1965). Wirtskontrollierte modifikation. Z. VerebLehre 96, 324–345.Google Scholar
Klein, A. & Sauerbier, W. (1965). Role of methylation in host-controlled modification of phage T1. Biochem. biophys. Res. Commun. 18, 440–445.CrossRefGoogle ScholarPubMed
Lederberg, S. (1966). Genetics of host-controlled restriction and modification of deoxyribo-nucleic acid in Escherichia coli. J. Bact. 91, 1029–1036.CrossRefGoogle Scholar
Lennox, E. S. (1955). Transduction of linked genetic characters of the host by bacteriophage P1. Virology 1, 190–206.CrossRefGoogle ScholarPubMed
Loper, J. C., Grabnar, M., Stahl, R. C., Hartman, Z. & Hartman, P. E. (1964). Genes and proteins involved in histidine biosynthesis in Salmonella. Brookhaven Symp. Biol. 17, 15–52.Google ScholarPubMed
Maccacaro, G. A. & Hayes, W. (1961). Pairing interaction as a basis for negative interference. Genet. Res. 2, 406–413.CrossRefGoogle Scholar
Schell, J. & Glover, S. W. (1966). On the localisation of a factor responsible for host controlled restriction in Escherichia coli K (P 1). Genet. Res. 7, 277–279.CrossRefGoogle Scholar
Smith, R. A., Shuster, C. W., Zimmerman, S. & Gunsalus, I. C. (1956). Serine synthesis in Escherichia coli. Bact. Proc. 15, 107.Google Scholar
Umbarger, H. E., Umbarger, M. A. & Siu, P. M. L. (1963). Biosynthesis of serine in Escherichia coli and Salmonella typhimurium. J. Bact. 85, 1431–1439.CrossRefGoogle ScholarPubMed
Wood, W. B. (1966). Host specificity of DNA produced by Escherichia coli. Bacterial mutations affecting the restriction and modification of DNA. J. molec. Biol. 16, 118–133.CrossRefGoogle ScholarPubMed