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Genetic studies on nucleolus organizer regions (NORs) in cattle

Published online by Cambridge University Press:  14 April 2009

B. Mayr ,
K. Gruber ,
G. Brem  and
G. Mayrhofer
B. Mayr
Affiliation:
Institute for Animal Breeding and Genetics, Veterinary University, Vienna, Austria
K. Gruber
Affiliation:
Ludwig Bollzmann Institute for Immuno- and Cytogenetic Research, Vienna, Austria
G. Brem
Affiliation:
Institute for Animal Breeding and Care, Ludwig Maximilian University, Munich, FRG
G. Mayrhofer
Affiliation:
Institute for Animal Breeding and Genetics, Veterinary University, Vienna, Austria

Summary

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Experimentally produced monozygotic twins, natural opposite sex blood chimeras (freemartins), and several pedigrees were used to evaluate the genetic influences on the nucleolus organizer region (NOR) patterns in cattle. In monozygotic twins, the NOR patterns of both twins are extremely similar. In chimeras, NOR patterns of genetically identical, peripheral blood lymphocytes (PBL) from the two partners resemble each other. In contrast, genetically different PBL (sib organ) differ significantly in the same environment. A high heritability of the individual NOR patterns is also demonstrated in our 23 pedigrees. In conclusion, our data demonstrate that variation in NOR expression is predominantly due to genetic factors.

Type
Research Article
Information
Genetics Research , Volume 53 , Issue 2 , April 1989 , pp. 111 - 118
Copyright
Copyright © Cambridge University Press 1989

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