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Genetic analysis of polymorphic proteins of the human malaria parasite Plasmodium falciparum

Published online by Cambridge University Press:  14 April 2009

Brian Fenton  and
David Walliker
Brian Fenton*
Affiliation:
Department of Genetics, University of Edinburgh, West Mains Road, Edinburgh EH9 3JN, Scotland, U.K.
David Walliker
Affiliation:
Department of Genetics, University of Edinburgh, West Mains Road, Edinburgh EH9 3JN, Scotland, U.K.
*
* Corresponding author.
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Summary

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Five polymorphic proteins, detected by two-dimensional electrophoresis, were analysed in the parents and progeny of a cross between two clones of the malaria parasite Plasmodium falciparum. The information obtained showed that different forms of each protein were determined by allelic variants of each respective gene. One protein was identified as the parasite enzyme adenosine deaminase. Recombinant parasites were produced at a higher than expected frequency.

Type
Research Article
Information
Genetics Research , Volume 55 , Issue 2 , April 1990 , pp. 81 - 86
Copyright
Copyright © Cambridge University Press 1990

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