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Genetic analysis of physiological homeostasis: glomerular filtration rate following saline loading in mice
Published online by Cambridge University Press: 14 April 2009
Summary
Saline loading caused an increase in glomerular filtration rate in RAP mice but not in CBA mice. On the basis of progeny testing of F 2 hybrids, backcrosses to CBA, and inbred lines derived from backcrosses to RAP, it was concluded that the difference between the strains RAP and CBA was probably largely accounted for by a single gene locus. The use of this gene in physiological investigations of the control of glomerular filtration rate is suggested.
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- Copyright © Cambridge University Press 1972
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