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Further evidence for the importance of parental source of the Xce allele in X chromosome inactivation

Published online by Cambridge University Press:  14 April 2009

Deborah J. Fowlis
Affiliation:
Department of Zoology, University of Edinburgh, West Mains Road, Edinburgh, EH9 3JT
John D. Ansell*
Affiliation:
Department of Zoology, University of Edinburgh, West Mains Road, Edinburgh, EH9 3JT
H. Spedding Micklem
Affiliation:
Department of Zoology, University of Edinburgh, West Mains Road, Edinburgh, EH9 3JT
*
Corresponding author.

Summary

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Using mice that were mosaics for both Xce and phosphoglycerate kinase (Pgk-1) alleles, we present further evidence that the parental source of the X chromosome may affect the probability of that X chromosome remaining active. The reciprocal cross differences in PGK-1 activity described here are intermediate between those published previously for other alleles of Xce.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1991

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