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The founder effect and response to artificial selection

Published online by Cambridge University Press:  14 April 2009

J. W. James
J. W. James
Affiliation:
School of Wool and Pastoral Sciences, The University of New South Wales, Kensington, Australia
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The response to selection in any line depends on the size of the initial sample by which the line is founded. For a single locus with additive gene action the effects of number of founders on early rate of response and on final limits are studied in relation to selection intensity and number of parents in the selected line. The reduction in total response caused by a small number of founders is greatest for large populations under intense selection, especially when the desirable alleles are rare in the base population. If these alleles are at high frequencies it is possible that a line which has gone through a bottleneck may be more sensitive to a reduced population size during subsequent selection than a line which has not. Under some conditions replicate selection lines founded with small samples are likely to be less variable in response than lines founded with moderately large samples.

Type
Research Article
Information
Genetics Research , Volume 16 , Issue 3 , December 1970 , pp. 241 - 250
Copyright
Copyright © Cambridge University Press 1970

References

REFERENCES

Falconer, D. S. (1960). An Introduction to Quantitative Genetics. Edinburgh: Oliver and Boyd.Google Scholar
Hill, W. G. & Robertson, A. (1966). The effect of linkage on limits to artificial selection. Genetical Research 8, 269–294.CrossRefGoogle ScholarPubMed
Jones, L. P., Frankham, R. & Barker, J. S. F. (1968). The effects of population size and selection intensity in selection for a quantitative character in Drosophila. II. Long-term response to selection. Genetical Research 12, 249–266.CrossRefGoogle Scholar
Kimura, M. (1957). Some problems of stochastic processes in genetics. Annals of Mathematical Statistics 28, 882–901.CrossRefGoogle Scholar
Kojima, K. (1961). Effects of dominance and size of population on response to mass selection. Genetical Research 2, 177–188.CrossRefGoogle Scholar
Latter, B. D. H. (1964). Selection for a threshold character in Drosophila. I. An analysis of the phenotypic variance on the underlying scale. Genetical Research 5, 198–210.CrossRefGoogle Scholar
Latter, B. D. H. (1965). Response to artificial selection due to autosomal genes of large effect. II. The effects of linkage on limits to selection in finite populations. Australian Journal of Biological Sciences 18, 1009–1023.CrossRefGoogle ScholarPubMed
Robertson, A. (1960). A theory of limits in artificial selection. Proceedings of the Royal Society, London, B 153, 234–249.Google Scholar
Robertson, A. (1966). Artificial selection in plants and animals. Proceedings of the Royal Society, London, B 164, 341–349.Google ScholarPubMed
Wright, S. (1931). Evolution in Mendelian populations. Genetics 16, 97–159.CrossRefGoogle ScholarPubMed