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A failure to induce heritable changes in four generations of the White Leghorn chicken by inter- and intra-specific blood transfusion*†

Published online by Cambridge University Press:  14 April 2009

I. L. Kosin  and
Masaru Kato
I. L. Kosin
Affiliation:
Washington State University, Pullman, Washington, U.S.A.
Masaru Kato
Affiliation:
Washington State University, Pullman, Washington, U.S.A.
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1. A three-year study was conducted to test the efficacy of inter- and intra-specific blood transfusions in domestic poultry for inducing heritable changes in the recipients. The latter were pure-bred White Leghorns. Pure-bred Broad Breasted Bronze turkeys and New Hampshire chickens served as blood donors to two distinct lines of recipients. All injections started when the recipient chicks were 2–5 days old. Altogether, more than 3000 chicks from blood injected lines were involved in the study, conducted between 1959 and 1961 and distributed between the parental and three subsequent generations. Each injected chick received a total of some 155 ml. of whole blood in the course of a five-month injection period. An adequate number of control (non-injected) birds was used throughout. Observations were made on plumage colour, body-weight, egg-weight, egg-shell colour, fertility and hatchability. Furthermore, blood plasma and muscle tissue of appropriate birds were subjected to immunological, chromatographic and electrophoretic analyses.

2. On the basis of all these criteria, no evidence of heritable shifts in the direction of the donor organism was discerned among birds belonging to either of the two treated lines.

Type
Research Article
Information
Genetics Research , Volume 4 , Issue 2 , July 1963 , pp. 221 - 239
Copyright
Copyright © Cambridge University Press 1963

References

REFERENCES

Astaurov, B. L., Bedniakova, T. A., Gintsburg, G. I., Zbirskii, I. B. & Ramenskaia, G. P. (1960). Opyt polucheniia nasledstvennykh izmenenii u tutovogo shelkopriada (Bomby xmori L.) posredstvom mezhlineinykh in'ektsii desoksiribonukleinovoi kisloty. [An experiment on the acquisition of heritable changes in the silkworm (Bombyxmori L.) by inter-line injections of desoxyribonucleic acid.] Dokl. Akad. Nauk S.S.S.R. 134, 449–452.Google Scholar
Avery, O. T., MacLeod, C. M. & McCarthy, M. (1944). Studies on the chemical nature of the substance inducing transformation of pneumococcal types. Induction of transformation by a desoxyribonucleic acid fraction isolated from pneumococcus type III. J. exp. Med. 79, 137–159.CrossRefGoogle ScholarPubMed
Bearn, J. G. & Kirby, K. S. (1959). Failure of deoxyribonucleic acid to produce pigment changes in the albino rat. Exp. Cell. Res. 17, 547–549.Google Scholar
Benoit, J., Leroy, P., Vendrely, C. & Vendrely, R. (1957). Des mutations somatiques dirigées sont-elles possible chez les oiseaux? C. R. Acad. Sci., Paris, 244, 2320–2321.Google Scholar
Bensch, K. G. & King, D. W. (1961). Incorporation of heterologous deoxyribonucleic acid into mammalian cells. Science, 133, 381–382.CrossRefGoogle ScholarPubMed
Boyden, A. (1953). Fifty years of systematic serology. Systematic Zool. 2, 19–30.CrossRefGoogle Scholar
Burger, R. E., Shoffner, R. N. & Roberts, C. W. (1961). Treatment of fowl sperm and developing embryos with deoxyribonucleic acid extracts. Poultry Sci. 40, 559–564.CrossRefGoogle Scholar
Buschinelli, A. (1961). Injeções periódical de sangue em aves e suas implicaçõ geneticas. [Periodic injections of blood into birds and their genetic implication.] Tese para o doutoramento em Ciencias. Facultade de Filisofia, Ciencias e Letras da Universidade de Sâo Paulo, Brazil. 142 pp.Google Scholar
Buzatti-Traverso, A. A. & Reichnitzer, A. B. (1953). Paper partition chromatography in taxonomic studies. Science, 117, 58–59.CrossRefGoogle Scholar
DeFalco, R. J. (1942). A serological study of some avian relationships. Biol. Bull., Wood's Hole, 83, 205–218.Google Scholar
Deutsch, H. F. and Goodloe, M.B.(1945). An electrophoretic survey of various animal plasmas. J. biol. Chem. 161, 1–20.CrossRefGoogle ScholarPubMed
Galton, F. (1871). Experiments in pangenesis, by breeding from rabbits of a pure variety, into whose circulation blood taken from other varieties had previously been largely transfused. Proc. roy. Soc. 19, 393–410.Google Scholar
Gershenzon, S. M. & Kiseleva, I. A. (1958). Vyzyvanie napravlennykh nasledstvennykh izmeninii u Drosophila melanogaster. [Induction of directed hereditary changes in Drosophila melanogaster.] Dokl. Akad. Nauk S.S.S.R. 123, 554–557.Google Scholar
Gromov, A. M. (1959). Izmeniniia u kur, voznikaiushchie podvliianiem perelivaniia chuzherodnoi krovi. [Changes induced in chickens by the transfusion of foreign blood.] Ptitsevodstvo, 9, 26–27.Google Scholar
Gromov, A. M. & Feoktistov, P. I. (1956). Izmenenie nasledstvennosti u kur posredstvom perelivaniia krovi. [Changes in the heredity of chickens by blood transfusion.] Ptilsevodstvo, 6, 42–45.Google Scholar
Hörstadius, S., Lorch, I. J. & Chabgaff, E. (1954). The effect of deoxyribonucleic acids extracted from sea urchin sperm on the development of sea urchin eggs. Exp. Cell. Res. 6, 440–452.Google Scholar
Kushner, H. F. (1957). The influence of metabolic factors on the heredity of animals. Proc. Internat. Genetics Symposia, Tokyo and Kyoto, Japan, pp. 515–519.Google Scholar
Kushner, H. F. (1958 a). Inheritance of changes in feathering pigmentation in fowls (hens) subjected to foreign blood transfusion. Proc. Xth Internat. Congress of Genetics, 2, 155.Google Scholar
Kushner, Kh. F. (1958 b). Nasledovanie u kur izmenenii v okraske opereniia, voznikshikh pod vliianiem perelivaniia chuzherodnoi krovi. [Inheritance of changes in the plumage colour of chickens subjected to foreign blood transfusion.] Zh. Obshch. Biolog. 19, 357–368.Google Scholar
Kushner, Kh. F., Tolokonntkova, E. V. & Moiseeva, I. G. (1959). Izmenenie okraski opereniia u potomstva kur v resul'tate vlivaniia im razlichnykh komponentov chuzherodnoi krovi. [Changes in the plumage colour of the progeny of chickens as a result of their injection with different components of foreign blood.] Dokl. Akad. Nauk S.S.S.R. 129, 674–677.Google Scholar
Leroy, P. (1962). Observations faites sur des poules ‘Rhode Island Red’ génétiquement contrôlées et sur leurs descendands de 1re et 2e générations après injections répétées de sang de pintade. C. R. Acad. Sci., Paris, 254, 756–758.Google Scholar
Leuchtenberger, C., Leuchtenberger, R. & Uyeki, E. (1958). Cytological and cyto-chemical changes in livers of white mice following intraperitoneal injections of DNA preparations from breast cancers of agouti C3H mice. Proc. nat. Acad. Sci., Wash., 44, 700–705.Google Scholar
Lysenko, T. D. (1946). Heredity and its Variability. King's Crown Press, Morningside Heights, N.Y., pp. 65.Google Scholar
Lysenko, T. D. (1956). O biologicheskom vide i vidoobrazovanii. [On species and speciation.] Agrobiologiia, No. 4, 3–30.Google Scholar
Mainaedi, D. (1958). Immunology and chromatography in taxonomic studies on gallinaceous birds. Nature, Lond., 182, 1388–1389.Google Scholar
Mainardi, D. (1959). Immunological distances among some gallinaceous birds. Nature, Lond., 184, 913–914.Google Scholar
Moore, D. H. (1945). Species differences in serum protein patterns. J. biol. Chem. 161, 21–32.Google Scholar
Novikov, B. G., Chepinoga, O. P. & Liubarskaia, M. A. (1961). Effekt in'ektsii chuzherodnoi DNK uutok. [The effect of injecting foreign DNA in ducks.] Zh. Obshch. Biolog. 22, 317–320.Google Scholar
Nuttall, G. H. F. (1901). The new biological test for blood in relation to zoological classification. Proc. roy. Soc. 69, 150–153.Google Scholar
Nuzhdik, N. E. edit. (1959). Nasledstvennost′ i Izmenchivost’ Rastenii, Zhivotnykh i Mikro-organizmov. [Heredity and Variability in Plants, Animals and Microorganisms.]Vols. 1 and 2. Akad. Nauk S.S.S.R. Moscow.Google Scholar
Ovenko, K. S. (1958). Vliiaet li perelivanie krovi na rost tsypliat? [Does the transfusion of blood affect the growth of chicks?] Ptitsevodstvo, 8, 38–39.Google Scholar
Penionzhkevich, E. E. (1961). Metody vyvedeniia i sovershenstvovaniia miaso-iaichnykh porod kur. [Methods of breeding and improving the dual-purpose breeds of chickens.] Trudy Vsesoiuz. Nauchno-issled. Inst. Ptitsev. 27, 3–14.Google Scholar
Penionzhkevich, E. E. & Mishin, G. A. (1959). Izmenenie nasledstvennosti u Belykh Legkhornov v resul'tate in'ektsii im krovi serykh tsesarok. [Changes in the heredity of White Leghorns as a result of injecting them with the blood of grey guinea-fowl.] Ptitsevodstvo, 8, 32–33.Google Scholar
Perry, T. L. & Walker, D. (1958). Failure of deoxyribonucleic acid to effect somatic transformation in the rat. Proc. Soc. exp. Biol., N.Y., 99, 717–720.CrossRefGoogle ScholarPubMed
Sibley, C. G. & Johnsgard, P. A. (1959). Variability in the electrophoretic patterns of avian serum proteins. Condor, 61, 85–95.Google Scholar
Sopikov, P. M. (1950). Novyi metod vegetativnoi gibridizatsii posredstvom perelivaniia krovi. [A new method of vegetative hybridization by blood transfusion.] Priroda, 39, 66.Google Scholar
Sopikov, P. M. (1954). Izmenenie nasledstvennosti putem parenteral'nogo vvedeniia krovi. [Changes in heredity by the parenteral administration of blood.] Agrobiologiia, 6, 34–45.Google Scholar
Sopikov, P. M. (1958). Izmenenie nasledstvennosti i povyshenie zhiznennosti zhivotnykh putem parenteral'nykh wedenii retsipientam krovi i drugikh tkanei. [Changes in heredity and increased vitality in animals by parenteral administration to recipients of blood and other tissues.] Trudy Vsesoiuz. Nauchno-issled. Inst. Ptitsev. 25, 101–132.Google Scholar
Sopikov, P. M. (1959). Izmenenie nasledstvennosti u zhivotnykh posredstvom perelivaniia krovi, implantatsii tkanei i nasledovannie priobretennykh prisnakov i svoistv. [Changes in the heredity of animals by blood transfusion, tissue implantation and the inheritance of acquired characters and traits.] Nasledstvennost′ i Izmenchivost′ Rastenii, Zhivotnykh i Mikroorganismov. [Heredity and variability in plants, animals and microorganisms J] Nuzhdin, N. E. edit. Acad. Nauk S.S.S.R., Moscow, 1, 554–560.Google Scholar
Sopikov, P. M. (1962). Alteración de ciertas propiedades y caracteres en las gallinas, por medio de transfusion parenteral de sangre y su fijación en als cr´as. [The alteration of certain properties and characters in fowls by means of parenteral transfusion of blood and their fixation in the offspring.] Memorias del XI (1958) Congreso Mundial de Avicultura, 109–116. (English summary on p. 748.)Google Scholar
Stroun, J. H., Stroun-Guttierre, L. R., Rossi, J. & Stroun, M. (1958). Modifications de la poule Leghorn traitée par de sang de pintade. Proc. Xth Internat. Congress of Genetics, 2, 280.Google Scholar
Svoboda, J. & HaŠKová, V. (1959). Failure to produce somatic changes between strains of ducks by means of specific DNA. Folia biol. (Prague), 5, 402–404.Google Scholar
Tigyi, A., Benedeczky, I. & LissáK, K. (1959). Studies on the modifying effect of isolated desoxyribonucleic acid in mammals. Acta biol. (Hungary), 10, 197–205.Google Scholar
Tolokonutkova, E. V.Moiseeva, I. G. (1958). Vliianie vvedeniia chuzherodnoikrovikuram na ikh potomstvo. [Injection of foreign blood into chickens—the effect on their progeny.] Trudy Inst. Genet. Akad. Nauk S.S.S.R., 24, 272–384.Google Scholar
Tolokoistntkova, E. V., Moiseeva, I. G. & Bogatybeva, S. A. (1961). Izmenenie okraski opereniia u kur v resul'tate wedeniia im razlichnykh komponentov chuzherodnoi krovi. [Changing the plumage of chickens by injecting them with various components of foreign blood.] Zh. Obshch. Biolog. 21, 66–73.Google Scholar
Stroun, J., Stroun-Guttières, Litza, Rossi, J. & Stroun, M. (1962). Modifications de la couleur du plumage provoqu´es chez la Poule Leghorn blanche par injections répétées de sang de pintade grise. Observations sur cinq générations. C. R. Acad. Sci., Paris, 255, 781–783.Google Scholar
Stroun, J., Stroun-Guttières, Litza, Rossi, J. & Steoun, M. (1962). Modifications de la couleur du plumage provoquées chez la Poule Leghorn blanche par injections répétées de sang de pintade grise. Caract`re héréditaire de ces modifications. C. R. Acad. Sci., Paris, 255, 1030–1032.Google Scholar
Penionzhkevich, E. E., Poletsky, V. A. & Nickolsky, B. S. (1962). Effect of Heterogeneous blood on recipient's organism under vegetative hybridization of farm poultry. Proc. XIIth World's Poultry Congress, 148–152.Google Scholar