Hostname: page-component-586b7cd67f-2brh9 Total loading time: 0 Render date: 2024-11-28T01:14:05.075Z Has data issue: false hasContentIssue false
  • English
  • Français

Evolution of amphimixis and recombination under fluctuating selection in one and many traits

Published online by Cambridge University Press:  14 April 2009

Alexey S. Kondrashov  and
Lev Yu. Yampolsky
Alexey S. Kondrashov*
Affiliation:
Section of Ecology and Systematics, Cornell University, Ithaca, NY 14853, USA
Lev Yu. Yampolsky
Affiliation:
Section of Ecology and Systematics, Cornell University, Ithaca, NY 14853, USA
*
*Corresponding author. Telephone: +1(607) 254-4221. Fax: + 1(607) 255-8088. e-mail: [email protected].
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Both stabilizing and directional selection acting on one or many quantitative traits usually reduce the genetic variance in a polymorphic population. Amphimixis and recombination restore the variance, pushing it closer to its value under linkage equilibrium. They thus increase the response of the population to fluctuating selection and decrease the genetic load when the mean phenotype is far from optimum. Amphimixis can have a short-term advantage over apomixis if selection fluctuates frequently and widely, so that every genotype often has a low fitness. Such selection causes high genetic variance due to frequent allele substitutions, and a high load even with amphimixis. Recombination in an amphimictic population is maintained only if selection is usually strong and effectively directional. A modifier allele causing free recombination can have a significant advantage only if fluctuations of selection are such that the load is substantial. With smaller fluctuations, an intermediate recombination rate can be established, either due to fixation of alleles that cause such a rate or due to the stable coexistence of alleles causing high and low recombination. If many traits simultaneously are under fluctuating selection, amphimixis and recombination can be maintained when selection associated with individual traits is weaker and the changes in their mean values are smaller than with a single trait. Still, the range of changes of the fitness optima in each trait must be at least of the order of the trait's standard deviation, and the total load must be high.

Type
Research Article
Information
Genetics Research , Volume 68 , Issue 2 , October 1996 , pp. 165 - 173
Copyright
Copyright © Cambridge University Press 1996

References

Barton, N. H., (1995). A general model for the evolution of recombination. Genetical Research 65, 123–144.Google Scholar
Bergman, A., & Feldman, M. W., (1990). More on selection for and against recombination. Theoretical Population Biology, 38, 68–92.CrossRefGoogle ScholarPubMed
Charlesworth, B., (1990). Mutation-selection balance and the evolutionary advantage of sex and recombination. Genetical Research 55, 199–221.Google Scholar
Charlesworth, B., (1993). Directional selection and the evolution of sex and recombination. Genetical Research 61, 205–224.CrossRefGoogle ScholarPubMed
Charlesworth, B., & Barton, N. H., (1996). Recombination load associated with selection for increased recombination. Genetical Research 67, 27–41.Google Scholar
Crow, J. F., (1988). The importance of recombination. In The Evolution of Sex: An Examination of Current Ideas (ed. Michod, R. E. & Levin, B. R.), pp. 56–73. Sunderland: Sinauer.Google Scholar
Crow, J. F., (1992). An advantage of sexual reproduction in a rapidly changing environment. Journal of Heredity 83, 169–173.CrossRefGoogle Scholar
Endler, J. A., (1986). Natural Selection in the Wild. Princeton, NJ: Princeton University Press.Google Scholar
Eshel, I., & Feldman, M. W., (1970). On the evolutionary effect of recombination. Theoretical Population Biology 1, 88–100.Google Scholar
Felsenstein, J., (1965). The effect of linkage on directional selection. Genetics 52, 349–363.CrossRefGoogle ScholarPubMed
Fraser, A. S., (1957). Simulation of genetic systems by automatic digital computers. II. Effects of linkage on rates of advance under selection. Australian Journal of Biological Science 10, 492–499.Google Scholar
Hamilton, W. D., Axelrod, R., & Tanese, R., (1990). Sexual reproduction as an adaptation to resist parasites: a review. Proceedings of the National Academy of Sciences of the USA 87, 3566–3573.CrossRefGoogle ScholarPubMed
Judson, O. P., (1995). Preserving genes: a model of the maintenance of genetic variation in a metapopulation under frequency-dependent selection. Genetical Research 65, 175–191.CrossRefGoogle Scholar
Karlin, S., & McGregor, J., (1972). Towards a theory of the evolution of modifier genes. Theoretical Population Biology 5, 59–105.Google Scholar
Kondrashov, A. S., (1984). Deleterious mutations as an evolutionary factor. I. The advantage of recombination. Genetical Research 44, 199–214.CrossRefGoogle Scholar
Kondrashov, A. S., (1993). Classification of hypotheses on the advantage of amphimixis. Journal of Heredity 84, 372–387.CrossRefGoogle ScholarPubMed
Kondrashov, A. S., & Turelli, M., (1992). Deleterious mutations, apparent stabilizing selection and maintenance of quantitative variation. Genetics 132, 603–618.Google Scholar
Kondrashov, A. S., & Yampolsky, L. Yu. (1996). High genetic variability under the balance between symmetric mutations and fluctuating stabilizing selection. Genetic Research 68, 157–164.CrossRefGoogle Scholar
Korol, A. B., & Preygel, I. A., (1989). The increase of recombination in the multilocus system under changing environment. Genetika 25, 923–931.(in Russian).Google Scholar
Korol, A. B., Preygel, I. A. & Preygel, S.I. (1994). Recombination, Variability and Evolution. London, Chapman & Hall.Google Scholar
Smith, J. Maynard, (1978). The Evolution of Sex. Cambridge: Cambridge University Press.Google Scholar
Smith, J. Maynard, (1980). Selection for recombination in a polygenic model. Genetical Research 35, 269–277.Google Scholar
Smith, J. Maynard, (1988). Selection for recombination in a polygenic model: the mechanism. Genetical Research 51, 59–63.Google Scholar
Shnol, E. E., & Kondrashov, A. S., (1993). Effect of selection on the phenotypic variance. Genetics 134, 995–996.Google Scholar
Treisman, M., (1976). The evolution of sexual reproduction: a model which assumes individual selection. Journal of Theoretical Biology, 60, 421–431.Google Scholar
Turelli, M., (1984). Heritable genetic variation via mutation-selection balance: Lerch's zeta meets the abdominal bristle. Theoretical Population Biology 25, 138–193.Google Scholar
Zhivotovsky, L. A., Feldman, M. W., & Christiansen, F. B., (1994). Evolution of recombination among multiple selected loci: a generalized reduction principle. Proceedings of the National Academy of Sciences of the USA 91, 1079–1083.Google Scholar