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Estimating the recombination parameter of a finite population model without selection

Published online by Cambridge University Press:  14 April 2009

Richard R. Hudson
Richard R. Hudson
Affiliation:
N.I.E.H.S., P.O. Box 12233, Research Triangle Park, N.C. 27709, U.S.A.
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Summary

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An estimator is proposed for the parameter C = 4Nc. where N is the population size and c is the recombination rate. The estimator is appropriate for use with sequence or restriction site data from random samples from within populations. Properties of the estimator are investigated for an infinite-sites neutral model using Monte Carlo simulations. The median and mode of the distribution of the estimator are close to the true value for all parameter values examined, but large data sets are required to obtain reliable estimates.

Type
Research Article
Information
Genetics Research , Volume 50 , Issue 3 , December 1987 , pp. 245 - 250
Copyright
Copyright © Cambridge University Press 1987

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