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The effects of the t-complex upon male reproduction are due to complex interactions between its several regions

Published online by Cambridge University Press:  14 April 2009

Craig Hammerberg
Craig Hammerberg
Affiliation:
Department of Human Genetics, Box 015, The University of Michigan Medical School, 1137 E. Catherine Street, Ann Arbor, Michigan 48109
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Summary

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The three major regions (T, tail-determining; A, abnormal transmission ration; L, embryonic lethality) of the t complex on the murine seventeenth chromosome can interact to influence male reproduction (Lyon & Mason, 1977; Hammerberg, 1981). Evidence is presented here that suggests: (1) the presence of a polymorphic system within the T region that influences quasi-sterility in the male; (2) the existence of enhancing factors of transmission ratio distortion; and (3) that preferential interactions between t-haplotypes are found to occur both cis and trans which influence transmission ratio distortion.

Type
Research Article
Information
Genetics Research , Volume 39 , Issue 3 , June 1982 , pp. 219 - 226
Copyright
Copyright © Cambridge University Press 1982

References

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