Hostname: page-component-78c5997874-g7gxr Total loading time: 0 Render date: 2024-11-09T15:55:46.258Z Has data issue: false hasContentIssue false
  • English
  • Français

The effect of selection for body weight on the skeletal variation of the mouse

Published online by Cambridge University Press:  14 April 2009

Gillian M. Truslove
Gillian M. Truslove
Affiliation:
Department of Human Genetics and Biometry, University College London, Wolfson House, 4, Stephenson Way, London NW1 2HE
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The incidence of many minor skeletal variants in the inbred mouse strain C57BL can be influenced by the diet on which the parents live: in many cases, the effect is mediated by a correlation with body size. This also seems to be true in Falconer's (1973) Q-strain in which body size has been increased or decreased by selection. However, there was so much heterogeneity between replicates within selection lines that variants influenced by body size could be detected as a group, but not identified individually.

Type
Research Article
Information
Genetics Research , Volume 28 , Issue 1 , August 1976 , pp. 1 - 10
Copyright
Copyright © Cambridge University Press 1976

References

REFERENCES

Berry, R. J. & Searle, A. G. (1963). Epigenetic polymorphism of the rodent skeleton. Proceedings of the Zoological Society of London 140, 577–615.Google Scholar
Deol, M. S. (1955). Genetical studies on the skeleton of the mouse. XIV. Minor variations of the skull. Journal of Genetics 53, 498–514.CrossRefGoogle Scholar
Deol, M. S. & Truslove, G. M. (1957). Genetical studies on the skeleton of the mouse. XX. Maternal physiology and variation in the skeleton of C57BL mice. Journal of Genetics 55, 288–312.Google Scholar
Falconer, D. S. (1973). Replicated selection for body weight in mice. Genetical Research 22, 291–321.CrossRefGoogle ScholarPubMed
Grüneberg, H. (1950). Genetical studies on the skeleton of the mouse. I. Minor variations of the vertebral column. Journal of Genetics 50, 112–141.CrossRefGoogle ScholarPubMed
Grüneberg, H. (1963). The Pathology of Development. Oxford: Blackwell Scientific Publications.Google Scholar
Howe, W. L. & Parsons, P. A. (1967). Genotype and environment in the determination of minor skeletal variants and body weight in mice. Journal of Embryology and Experimental Morphology 17, 283–292.Google Scholar
Levin, E. Y. & Flyger, V. (1971). Uroporphyrinogen III cosynthetase activity in the fox squirrel (Sciurus niger). Science 174, 59–60.Google Scholar
Searle, A. G. (1954 a). Genetical studies on the skeleton of the mouse. IX. Causes of skeletal variation within pure lines. Journal of Genetics 52, 68–102.Google Scholar
Searle, A. G. (1954 b). Genetical studies on the skeleton of the mouse. X. Rarer variants in the A and C57BL pure lines. Journal of Genetics 52, 103–110.Google Scholar
Searle, A. C. (1954 c). Genetical studies on the skeleton of the mouse. XI. The influence of diet on variation within pure lines. Journal of Genetics 52, 413–424.CrossRefGoogle Scholar
Wickramaratne, G. A. de S. (1974). The ‘skeletal profile’ and dentition of some inbred strains of mice. Journal of Anatomy 117, 565–573.Google Scholar