Published online by Cambridge University Press: 14 April 2009
Using seven newly induced duplications, three Minute loci have been located cytologically: M(3)hS 37 in 65F10–11; 66A (a new Minute locus), M(3)i in 67C, and M(3)hy in 68F; 69F. M(3)hS 37 and M(3)hy were previously thought to be allelic because they do not complement for lethality. The finding of Minute mutations with additive or synergistic rather than epistatic interactions makes us suspect that some other Minute mutations have been erroneously called allelic. The involvement of Minute loci in more than one biochemical pathway is discussed in view of the existence of synergistic interactions and of Minute loci without known mutant alleles.