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Conditional induction of λ prophage in exrA mutants of Escherichia coli

Published online by Cambridge University Press:  14 April 2009

J. J. Donch ,
M. H. L. Green  and
J. Greenberg
J. J. Donch
Affiliation:
Palo Alto Medical Research Foundation, Pala Alto, California 94301
M. H. L. Green
Affiliation:
Palo Alto Medical Research Foundation, Pala Alto, California 94301
J. Greenberg
Affiliation:
Palo Alto Medical Research Foundation, Pala Alto, California 94301
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Summary

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Strains of Escherichia coli which contain the UV sensitivity gene exrA, repress UV induction of λ prophage in a novel manner. While exrA+ strains can be induced by UV irradiation and express this induction in a 2 h period, exrA mutants delay the expression of induction for almost 4 h, and the induction maximum is approximately 10% of the wild-type value. The kinetics of the delayed induction and superinfection experiments indicate that the lifting of immunity and induction of λ prophage occur simultaneously.

Type
Short Papers
Information
Genetics Research , Volume 17 , Issue 2 , April 1971 , pp. 161 - 163
Copyright
Copyright © Cambridge University Press 1971

References

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