Hostname: page-component-586b7cd67f-rdxmf Total loading time: 0 Render date: 2024-11-24T12:11:33.006Z Has data issue: false hasContentIssue false
  • English
  • Français

A comparative genetical study on DDT resistance in adults and larvae of the mosquito Aedes aegypti L

Published online by Cambridge University Press:  14 April 2009

R. J. Wood
R. J. Wood
Affiliation:
Department of Zoology, University of Manchester
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Inheritance of DDT resistance has been studied in crosses between the highly resistant ‘T’ strain of A. aegypti (constituted by inbreeding from the TRINIDAD DDT-resistant stock) and the ‘64’ susceptible strain.

Larval DDT resistance derives from a major gene RDDT1 on linkage group II, the order being RDDT1–s–y. Linkage group III may also contribute to larval resistance. Linkage group I makes no contribution.

Adult DDT resistance derives from a major gene RDDT2, 18·2 ± 2·1 units from the market blt on linkage group III. Linkage group II has no influence on adult resistance.

Selection with DDT to retain only RDDT1/+ segregants in larvae of backcrosses RDDT1/+×+/+ did not increase resistance in resulting adults, confirming the difference in genetic mechanism at the two stages.

The F1 progenies from reciprocal crosses between ‘T’ and ‘64’ differed slightly but significantly in larval resistance, modifying the influence of the major gene RDDT1 in the heterozygote.

The early developmental stages of the RDDT1/+ phenotype (up to the fourth larval stage) were more viable than the +/+ phenotype in backcross segregation. The difference in mortality probably exceeded 30%.

Type
Research Article
Information
Genetics Research , Volume 10 , Issue 3 , December 1967 , pp. 219 - 228
Copyright
Copyright © Cambridge University Press 1967

References

REFERENCES

Abedi, Z. H., Duffy, J. R. & Brown, A. W. A. (1963). Dehydrochlorination and DDT resistance in Aedes aegypti. J. Econ. Ent. 56, 511–517.CrossRefGoogle Scholar
Bailey, N. T. J. (1961). Mathematical Theory of Genetic Linkage. London: Oxford University Press.Google Scholar
Brown, A. W. A. & Abedi, Z. H. (1962). Genetics of DDT-resistance in several strains of Aedes aegypti. Can. J. Genet. Cytol. 4, 319–332.CrossRefGoogle ScholarPubMed
Chattoraj, A. N. & Brown, A. W. A. (1960). Internal DDE production by normal and DDT-resistant larvae of Aedes aegypti. J. econ. Ent. 53, 1049–1051.CrossRefGoogle Scholar
Coker, W. Z. (1966). Linkage of the DDT-resistance gene in some strains of Aedes aegypti (L.). Ann. trop. Med. Parasit. 50, 347–356.CrossRefGoogle Scholar
Hickey, W. A. & Craig, G. B. Jr (1966). Genetic distortion of sex ratio in a mosquito, Aedes aegypti. Genetics, 53, 1177–1196.CrossRefGoogle Scholar
Kimura, T. & Brown, A. W. A. (1964). DDT-dehydrochlorinase in Aedes aegypti. J. econ. Ent. 57, 710–716.CrossRefGoogle Scholar
Klassen, W. & Brown, A. W. A. (1964). Genetics of insecticide resistance and several visible mutants in Aedes aegypti. Can. J. Genet. Cytol. 6, 61–73.CrossRefGoogle ScholarPubMed
Pillai, M. K. K. & Brown, A. W. A. (1965). Physiological and genetical studies on resistance to DDT substitutes in Aedes aegypti. J. econ. Ent. 58, 255–266.CrossRefGoogle ScholarPubMed
Wood, R. J. (1961). Biological and genetical studies on sex ratio in DDT-resistant and susceptible strains of Aedes aegypti (L.). Genet. agr. 13, 287–307.Google Scholar
Wood, R. J. (1962). DDT-resistance and larval development in Aedes aegypti (Linnaeus). The length of larval development and adult resistance in the Trinidad strain. Ann. trop. Med. Parasit. 56, 450–456.CrossRefGoogle ScholarPubMed
Wood, R. J. (1965). A genetical study on DDT-resistance in the Trinidad strain of Aedes aegypti (L.). Bull. Wld Hlth Org. 32, 563–574.Google Scholar
Wood, R. J. (1967). The use of discriminating concentrations in genetical studies on DDT-resistance in larval Aedes aegypti (L.). Bull. Wld Hlth Org. (in press).Google ScholarPubMed
World Health Organization (1963). Insecticide resistance and vector control: 13th Rep. Expert Comm. Insecticides. Tech. Rep. Ser. Wld Hlth Org. 265, 41–56.Google Scholar