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Characterization of an antibiotic resistance plasmid pAV5 and its constituent replicons in Acinetobacter calcoaceticus

Published online by Cambridge University Press:  14 April 2009

Mark Divers ,
Edward Hinchliffe  and
Alan Vivian
Mark Divers
Affiliation:
School of Biological Sciences and Environmental Health, Thames Polytechnic, Wellington Street, London, SE18 6PF
Edward Hinchliffe
Affiliation:
School of Biological Sciences and Environmental Health, Thames Polytechnic, Wellington Street, London, SE18 6PF
Alan Vivian
Affiliation:
School of Biological Sciences and Environmental Health, Thames Polytechnic, Wellington Street, London, SE18 6PF
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Summary

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A non-transmissible plasmid, pAV5, was isolated from a hospital strain of Acinetobacter calcoaceticus, JC17. pAV5 confers resistance to the antibiotics tetracycline and neomycin in the genetically characterized strain of A. calcoaceticus EBF 65/65. Transfer of pAV5 can be mediated by the sex factors pAV1 and R751; transfer is occasionally associated with the segregation of the resistance determinants amongst the transconjugants. Phenotypic dissociation of pAV5 corresponds with the formation of two independent plasmids designated pAV51 and pAV52 mediating resistance to neomycin and tetracycline respectively.

Type
Research Article
Information
Genetics Research , Volume 44 , Issue 1 , August 1984 , pp. 1 - 9
Copyright
Copyright © Cambridge University Press 1984

References

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