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Associations between allozyme loci and gene arrangements due to hitch-hiking effects of new inversions

Published online by Cambridge University Press:  14 April 2009

K. Ishii  and
B. Charlesworth
K. Ishii
Affiliation:
School of Biological Sciences, University of Sussex, Brighton BN1 9QG, Sussex
B. Charlesworth
Affiliation:
School of Biological Sciences, University of Sussex, Brighton BN1 9QG, Sussex
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Summary

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This paper examines the hypothesis that the associations between alleles at allozyme loci and gene arrangements, which are observed in many Drosophila populations, result from inversions remaining associated with the alleles contained in the gametes in which they originally occurred. The effects of double crossing over in heterokaryotypes and of selection at loci linked to the allozyme loci, which are themselves assumed to be neutral, are studied theoretically. It is concluded that selection at linked loci is unlikely to have an important effect in retarding the decay of this type of association. The literature on associations between allozymes and gene arrangements is surveyed, and it is concluded that a ‘neutralist’ explanation of this sort cannot be excluded, except possibly in some cases where the allozyme locus is outside the inversion breakpoints and crosses over with measurable frequency in heterokaryotypes.

Type
Research Article
Information
Genetics Research , Volume 30 , Issue 2 , October 1977 , pp. 93 - 106
Copyright
Copyright © Cambridge University Press 1977

References

REFERENCES

Charlesworth, B. (1974). Inversion polymorphism in a two-locus genetic system. Genetical Research 23, 259–280.CrossRefGoogle Scholar
Charlesworth, B., Charlesworth, D. & Loukas, M. (1976). Linkage disequilibrium studies on D. subobscura populations. Drosophila Information Service 52 (In the Press).Google Scholar
Chovnick, A. (1973), Gene conversion and transfer of genetic information within the inverted region of inversion heterozygotes. Genetics 75, 123–131.CrossRefGoogle ScholarPubMed
Chovnick, A., Ballantyne, G. H. & Holm, D. G. (1971). Studies on gene conversion and its relationship to linked exchange in Drosophila melanogaster. Genetics 69, 179–209.CrossRefGoogle ScholarPubMed
Kojima, K., Gillespie, J. H. & Tobari, Y. N. (1970). A profile of Drosophila species enzymes assayed by electrophoresis. I. Number of alleles, heterozygosities, and linkage disequilibrium in glucose-metabolizing systems and some other enzymes. Biochemical Genetics 4, 627–637.CrossRefGoogle ScholarPubMed
Langley, C. H., Tobari, Y. N. & Kojima, K. (1974). Linkage disequilibrium in natural populations of Drosophila melanogaster. Genetics 78, 921–936.CrossRefGoogle ScholarPubMed
Levine, R. P. (1956). Crossing over and inversions in coadapted systems. American Naturalist 90, 41–45.CrossRefGoogle Scholar
Lewontin, R. C. (1974). The Genetic Basis of Evolutionary Change. New York: Columbia University Press.Google Scholar
Maynard Smith, J. & Haigh, J. (1974). The hitch-hiking effect of a favourable gene. Genetical Research 23, 23–35.CrossRefGoogle Scholar
Mukai, T., Mettler, L. E. & Chigusa, S. I. (1971). Linkage disequilibrium in a local population of Drosophila melanogaster. Proceedings of the National Academy of Sciences, U.S.A. 68, 1056–1069.CrossRefGoogle Scholar
Mukai, T., Watanabe, T. K. & Yamaguchi, O. (1974). The genetic structure of natural populations of Drosophila melanogaster. XII. Linkage disequilibrium in a large local population. Genetics 77, 771–793.CrossRefGoogle Scholar
Nei, M. & Li, W. H. (1975). Probability of identical monomorphism in related species. Genetical Research 26, 31–43.CrossRefGoogle ScholarPubMed
Payne, F. (1924). Crossover modifiers in the third chromosome of Drosophila melanogaster. Genetics 9, 327–342.CrossRefGoogle ScholarPubMed
Prakash, S. (1974). Gene differences between the sex ratio and standard gene arrangements of the X chromosome and linkage disequilibrium between loci in the standard gene arrangement of Drosophila pseudoobscura. Genetics 77, 795–804.CrossRefGoogle ScholarPubMed
Prakash, S. & Levitan, M. (1973). Associations of alleles of the Esterase-1 locus with gene arrangements of the left arm of the second chromosome in Drosophila robusta. Genetics 75, 371–379.CrossRefGoogle ScholarPubMed
Prakash, S. & Lewontin, R. C. (1968). A molecular approach to the study of genie heterozygosity in natural populations. III. Direct evidence of coadaptation in gene arrangements of Drosophila. Proceedings of the National Academy of Sciences, U.S.A. 59, 398–405.CrossRefGoogle Scholar
Prakash, S. & Lewontin, R. C. (1971). A molecular approach to the study of genie heterozygosity in natural populations. V. Further direct evidence of coadaptation in inversions of Drosophila. Genetics 69, 405–408CrossRefGoogle Scholar
Prakash, S. & Merritt, R. B. (1972). Direct evidence of genie differentiation between sex ratio and standard gene arrangements of X chromosome in Drosophila pseudoobscura. Genetics 72, 169–175.CrossRefGoogle Scholar
Sheppard, P. M. (1975). Natural Selection and Heredity (4th edn.) London: Hutchinson.Google Scholar
Spurway, H. & Philip, U. (1952). Genetics and cytology of Drosophila subobscura. Journal of Genetics 51, 198–215.CrossRefGoogle Scholar
Sturtevant, A. H. (1931). Known and probably inverted sections of the autosomes of Drosophila melanogaster. In Contributions to the Genetics of Certain Chromosome Anomalies in Drosophila melanogaster (A. H. Sturtevant and T. Dobzhansky), pp. 1–27. Washington: Carnegie Institution Publ. No. 421.Google Scholar
Sturtevant, A. H. & Beadle, G. W. (1936). The relations of inversions in the X chromosome of Drosophila melanogaster to crossing over and disjunction. Genetics 21, 544–604.CrossRefGoogle ScholarPubMed
Watanabe, T. K. & Watanabe, T. (1977). Enzyme and chromosome polymorphisms in Japanese natural populations of Drosophila melanogaster. Genetics 85, 319–329.CrossRefGoogle ScholarPubMed
Yardley, D. (1974). Linkage analysis of α-amylase in D. pseudoobscura. Drosophila Information Service 51, 25.Google Scholar