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hCG production and activity during pregnancy

Published online by Cambridge University Press:  25 July 2001

H S Randeva
Affiliation:
The Sir Quinton Hazel Molecular Medicine Research Centre, Department of Biological Sciences, University of Warwick, Coventry
A Jackson
Affiliation:
The Sir Quinton Hazel Molecular Medicine Research Centre, Department of Biological Sciences, University of Warwick, Coventry
E Karteris
Affiliation:
The Sir Quinton Hazel Molecular Medicine Research Centre, Department of Biological Sciences, University of Warwick, Coventry
E W Hillhouse
Affiliation:
The Sir Quinton Hazel Molecular Medicine Research Centre, Department of Biological Sciences, University of Warwick, Coventry

Abstract

Human chorionic gonadotropin (hCG) has an essential role in early pregnancy. It is a member of the glycoprotein hormone family also comprising the pituitary derived follicle stimulating hormone (FSH), luteinizing hormone (LH) and thyroid stimulating hormone (TSH). Each hormone consists of a non-covalently bound α and β subunit. Within a species the α subunit is identical and hormone specificity is determined by the unique β subunit.

Type
Research Article
Copyright
© 2001 Cambridge University Press

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