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Atrial natriuretic peptide during human pregnancy and puerperium
Published online by Cambridge University Press: 10 October 2008
Extract
In 1981 De Bold and colleagues demonstrated that when extracts of atrial tissue were given intravenously to rats a large diuresis and natriuresis occured promptly. The structure of the hormone concerned, atrial natriuretic peptide (ANP), was elucidated in 1983. Since then, ANP has received attention as a potentially important mediator in the homoeostasis of sodium and fluid volume.
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