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Prenatal diagnosis using fetal cells in the maternal circulation

Published online by Cambridge University Press:  10 October 2008

D Gänshirt ,
HSP Garritsen  and
W Holzgreve
D Gänshirt*
Affiliation:
Departments of Obstetrics and Gynaecology, University of Münster, Germany
HSP Garritsen
Affiliation:
Transfusion Medicine, University of Münster, Germany.
W Holzgreve
Affiliation:
Departments of Obstetrics and Gynaecology, University of Münster, Germany
*
Dr D Gänshirt, Pränatale Medizin, Zentrum für Frauenheilkunde, Technologiehof, Mendelstr. 11, D-48149 Münster, Germany.
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Extract

Since the introduction of ultrasound into obstetrics during the 1960s, there has been rapid progress in the detection of genetic and nongenetic defects in utero. With the development of sampling procedures like amniocentesis, chorionic villus sampling (CVS) and fetal blood sampling, the obstetrician has been able to obtain fetal tissue and the parallel improvement in laboratory techniques has allowed the diagnosis of chromosomal anomalies and single gene defects from fetal cells. Amniocentesis and CVS have become well established techniques for routine prenatal diagnosis of chromosomal and metabolic disorders and fetal tissue is now accessible throughout all three trimesters.

Type
Articles
Information
Fetal and Maternal Medicine Review , Volume 7 , Issue 2 , May 1995 , pp. 77 - 86
Copyright
Copyright © Cambridge University Press 1995

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