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Genetically modified mouse models in studies on cutaneous wound healing

Published online by Cambridge University Press:  10 January 2001

Annette Scheid ,
Martin Meuli ,
Max Gassmann  and
Roland H. Wenger
Annette Scheid
Affiliation:
Department of Surgery, University Children's Hospital of Zürich, Institute of Physiology, University of Zürich-Irchel, CH-8000 Zürich, Switzerland and Institute of Physiology, Medical University Lübeck, D-23538 Lübeck, Germany
Martin Meuli
Affiliation:
Department of Surgery, University Children's Hospital of Zürich, Institute of Physiology, University of Zürich-Irchel, CH-8000 Zürich, Switzerland and Institute of Physiology, Medical University Lübeck, D-23538 Lübeck, Germany
Max Gassmann
Affiliation:
Department of Surgery, University Children's Hospital of Zürich, Institute of Physiology, University of Zürich-Irchel, CH-8000 Zürich, Switzerland and Institute of Physiology, Medical University Lübeck, D-23538 Lübeck, Germany
Roland H. Wenger
Affiliation:
Department of Surgery, University Children's Hospital of Zürich, Institute of Physiology, University of Zürich-Irchel, CH-8000 Zürich, Switzerland and Institute of Physiology, Medical University Lübeck, D-23538 Lübeck, Germany
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Abstract

Genetically modified mice have become an invaluable tool in modern biomedical and basic research. This review provides an overview of knockout and transgenic mice studied with regard to their cutaneous wound healing properties. In addition, several gene transfer studies are briefly introduced, which have further highlighted our knowledge on individual gene function in wound healing

Type
Research Article
Information
Experimental Physiology , Volume 85 , Issue 6 , November 2000 , pp. 687 - 704
Copyright
© The Physiological Society 2000

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