Hostname: page-component-586b7cd67f-t8hqh Total loading time: 0 Render date: 2024-11-28T09:34:59.934Z Has data issue: false hasContentIssue false
  • English
  • Français

Recent advances in gene therapy with skin cells

Published online by Cambridge University Press:  23 July 2002

MARCELA DEL RIO ,
FERNANDO LARCHER  and
JOSÉ LUIS JORCANO
MARCELA DEL RIO
Affiliation:
Project of Cell and Molecular Biology and Gene Therapy, CIEMAT, Avenida Complutense 22, 28040 Madrid, Spain and Fundacion Marcelino Botín for Gene Therapy. E-mail: [email protected]
FERNANDO LARCHER
Affiliation:
Project of Cell and Molecular Biology and Gene Therapy, CIEMAT, Avenida Complutense 22, 28040 Madrid, Spain and Fundacion Marcelino Botín for Gene Therapy. E-mail: [email protected]
JOSÉ LUIS JORCANO
Affiliation:
Project of Cell and Molecular Biology and Gene Therapy, CIEMAT, Avenida Complutense 22, 28040 Madrid, Spain and Fundacion Marcelino Botín for Gene Therapy. E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Somatic gene therapy remains a promising therapeutic approach for both inherited and acquired disorders. Among the tissues amenable to gene therapy, the skin, and particularly the epidermal cells, present several features advantageous for genetic manipulation and monitoring of therapeutic effects. Candidate diseases for cutaneous gene therapy not only involve skin defects but also systemic abnormalities. The robust basic and pre-clinical data gathered during the last few years have allowed the imminent launching of keratinocyte-based gene therapy with applications to patients.

Type
Research Article
Information
European Review , Volume 10 , Issue 3 , July 2002 , pp. 369 - 388
Copyright
© Academia Europaea 2002

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)