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The WHO-5 well-being scale and its correlation to depressive and manic symptoms among outpatients with bipolar disorder or unipolar depression

Published online by Cambridge University Press:  13 August 2021

S. Straszek ,
A.-E. Christensen ,
R. Licht ,
S. Østergaard  and
R. Ernst Nielsen
S. Straszek*
Affiliation:
Research And Treatment Programme For Bipolar Disorder, Psychiatry - Aalborg Úniversity Hospital, Aalborg, Denmark Department Of Clinical Medicine, Aalborg University, Aalborg, Denmark
A.-E. Christensen
Affiliation:
Unit For Psychiatric Research, Psychiatry - Aalborg University Hospital, Aalborg, Denmark
R. Licht
Affiliation:
Department Of Clinical Medicine, Aalborg University, Aalborg, Denmark Unit For Psychiatric Research, Psychiatry - Aalborg University Hospital, Aalborg, Denmark
S. Østergaard
Affiliation:
Department Of Clinical Medicine, Aarhus University, Aarhus, Denmark Department Of Affective Disorders, Aarhus University Hospital - Psychiatry, Aarhus, Denmark
R. Ernst Nielsen
Affiliation:
Department Of Clinical Medicine, Aalborg University, Aalborg, Denmark Psychiatry, Aalborg University Hospital, Aalborg, Denmark
*
*Corresponding author.

Abstract

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Introduction

There is a lack of longitudinal studies of patients with bipolar disorder (BD) or unipolar depression (UD) in terms of psychological well-being as measured by the WHO-5 and the correlation to symptom scores. It is of interest to investigate whether the WHO-5 is useful in monitoring patients with mood disorders over time, as a tool in measurement-based care, and as a supplement to other psychometric measures.

Objectives

In this study we investigate the correlation at baseline between the depressive symptom scores according to the 6-item Hamilton Depression Score (HDS-6) and the WHO-5 scores in outpatients treated for BD or UD. Furthermore, in patients with BD we investigate correlations between manic symptom scores according to the modified Bech-Rafaelsen Mania Scale (MAS-M) and the WHO-5 scores. Lastly, in patients with BD or UD, we investigate the correlations between endpoint-baseline change in WHO-5 and change in MAS-M and HDS-6.

Methods

A longitudinal study of 200 outpatients diagnosed and treated for either BD or UD. Patients will be measured at baseline and at least four weeks later. Baseline data are presented as frequencies, means and standard deviations or medians with interquartile ranges as appropriate. All correlations are presented as scatter plots and a Spearman correlation analysis

Results

The study is ongoing, but the results will be available for presentation at the EPA in 2021.

Conclusions

The WHO-5 may represent a relevant outcome measure in the treatment of BD and UD.

Disclosure

No significant relationships.

Keywords

bipolar disorderwho-5quality of lifeunipolar depression
Type
Abstract
Information
European Psychiatry , Volume 64 , Special Issue S1: Abstracts of the 29th European Congress of Psychiatry , April 2021 , pp. S76
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of the European Psychiatric Association
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