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Tokyo Teen Cohort study: a prospective cohort study on general population of adolescents

Published online by Cambridge University Press:  19 July 2023

S. Ando ,
A. Nishida ,
S. Yamasaki ,
K. Endo ,
M. Hiraiwa-Hasegawa  and
K. Kasai
S. Ando*
Affiliation:
The University of Tokyo
A. Nishida
Affiliation:
Tokyo Metropolitan Institute of Medical Science, Tokyo
S. Yamasaki
Affiliation:
Tokyo Metropolitan Institute of Medical Science, Tokyo
K. Endo
Affiliation:
Tokyo Metropolitan Institute of Medical Science, Tokyo
M. Hiraiwa-Hasegawa
Affiliation:
SOKENDAI, Kanagawa, Japan
K. Kasai
Affiliation:
The University of Tokyo
*
*Corresponding author.

Abstract

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Introduction

Adolescence is the period when many mental disorders have their peaks of onsets. Investigation into adolescent mental health problems and their risk factors is required, but there has been few prospective cohort studies on adolescent mental health.

Objectives

This study aimed to prospectively reveal the developmental trajectory of physical and mental health in adolescence, and to investigate factors associated with the trajectory.

Methods

We launched a prospective cohort study (Tokyo Teen Cohort: TTC) on general population of adolescents at three municipalities in metropolitan area in Tokyo, Japan. Using the resident register, we recruited 10-year-old children from the community between 2012 and 2015. The second, third, and fourth wave of data collection were conducted at 12, 14, 16 years of age, respectively. We collected multidisciplinary data including mental health by self-report questionnaire and home-visit interview. Further, we have launched two subsample studies which focus on biological measures such as brain MRI, EEG, and sex hormones. TTC is based at three research institutes, and ethics approval has been granted by all of the three institutions.

Results

A total of 3171 children participated the TTC. Of those, 3007 children participated in the second wave of data collection (follow-up rate: 94.8). The third and fourth wave of data collection were completed and more than 80% of children continued to participate in TTC. More than 300 children participated in the two subsample studies. More than 30 papers were already published, and many national/international research collaborations have started.

Conclusions

The fifth wave of data collection at 20 years of age is being currently conducted. Further national/international collaborations are expected to examine cultural effects on mental health of adolescents.

Disclosure of Interest

None Declared

Type
Abstract
Information
European Psychiatry , Volume 66 , Special Issue S1: Abstracts of the 31st European Congress of Psychiatry , March 2023 , pp. S465
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2023. Published by Cambridge University Press on behalf of the European Psychiatric Association
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