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Specifics of depression in epilepsy

Published online by Cambridge University Press:  01 September 2022

V. Mitikhin  and
M. Kuzminova
V. Mitikhin*
Affiliation:
FSBSI “Mental Health Research Centre”, Department Of Mental Health Services, Moscow, Russian Federation
M. Kuzminova
Affiliation:
FSBSI “Mental Health Research Centre”, Department Of Mental Health Services, Moscow, Russian Federation
*
*Corresponding author.

Abstract

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Introduction

The strong comorbidity between depression and epilepsy is widely acknowledged. However, depression in epilepsy can manifest atypically, leading to its low detection rate and lack of access to treatment in patients with epilepsy

Objectives

To study the specifics and pattern of depression in epilepsy for its timely diagnosis and therapy and to prevent suicide risk and improve the quality of life in patients with epilepsy

Methods

Clinical, statistical, psychometric. A total of 149 patients, mean age 45.0 ± 11.7 years, 74 males, 75 females, were examined

Results

It was found that depression was manifested in 46.3% of patients before the onset of epileptic seizures, and in 20.8% of patients it developed after treatment with some AEDs. The incidence of symptoms characteristic of depression in epilepsy, such as unstable mood, irritability, euphoria, episodes of pain and sleep disturbances, and its’ impact on the quality of life in patients with epilepsy were analysed. Gender differences were identified for a range of symptoms

Conclusions

The authors expanded their understanding of the clinical specifics of depressive manifestations in patients with epilepsy to allow timely detection and medical and rehabilitative care for these patients

Disclosure

No significant relationships.

Keywords

comorbidityDepressionepilepsy
Type
Abstract
Information
European Psychiatry , Volume 65 , Special Issue S1: Abstracts of the 30th European Congress of Psychiatry , June 2022 , pp. S147
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of the European Psychiatric Association
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