Hostname: page-component-cd9895bd7-p9bg8 Total loading time: 0 Render date: 2024-12-27T02:42:58.149Z Has data issue: false hasContentIssue false

Sleep, morning alertness and quality of life in subjects treated with zopiclone and in good sleepers. Study comparing 167 patients and 381 good sleepers

Published online by Cambridge University Press:  16 April 2020

D Léger
Affiliation:
Unité de Sommeil, Hôtel-Dieu de Paris, I place du Parvis-Notre-Dame, 75181Paris cedex 04, France
C Janus
Affiliation:
Théraplix, 46-52 rue Albert, 75013Paris, France
A Pellois
Affiliation:
Théraplix, 46-52 rue Albert, 75013Paris, France
MA Quera-Salva
Affiliation:
Unité de Sommeil, Hôpital Raymond-Poincaré, 104 boulevard Raymond Poincaré, 92380Garches, France
JP Dreyfus
Affiliation:
Département Médical Sofres, 16 rue Barbès, 92129Montrouge cedex, France
Get access

Summary

From 20,000 households regularly surveyed by a national survey institute (Sofres), two groups were selected and questioned (using a 23-item questionnaire) about sleep vigilance and quality of life. The first group was composed of insomniacs using zopiclone for the last 12 months and no other CNS treatments (167 subjects). The second group was composed of 381 “good sleepers” selected as having no or occasionally one sleep disturbance in the last 12 months. No difference was found between the two groups in average total sleep time. Sleep disturbances were statistically equal in the two groups except for difficulties in initiating sleep which is more present for zopiclone users (13% vs 3%). Vigilance was mostly comparable in both groups.Five aspects of quality of life explored by the questionnaires (the professional, relational and sentimental, domestic, leisure and safety aspects) appeared to be comparable in the two groups.

Type
Research Article
Copyright
Copyright © Elsevier, Paris 1995

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Addison, RGThorpy, MJRoehrs, TASleep: wake complaints in the general population. Sleep Res 1991; 20: 112Google Scholar
Aldrich, MSAutomobile accidents in patients with sleep disorders. Sleep 1989; 12: 487–94CrossRefGoogle ScholarPubMed
Baiter, MBUhlenhuth, EHNew epidemiologic findings about in-somnia and its treatment. J Clin Psychiatry 1992; 53(suppl 12):34–9Google Scholar
Carskadon, MADement, WCMiller, MMSelf reports versus sleep laboratory findings in 122 drug-free subjects with complaints of chronic insomnia. Am J Psychiatry 1976; 133: 1382–88Google ScholarPubMed
Gallop organization Sleep in America Princeton, NJ: The Gallop Organization, 1991 130Google Scholar
Gillin, JCByerley, WFDrug therapy: The diagnosis and management of insomnia. N Engl J Med 1990; 322: 239–48Google ScholarPubMed
Goldenberg, FHindmarch, JJoyce, CRBLe Gal, MPartinen, MPilate, CZopiclone, sleep and health-related quality of life. Human Psychopharmacol 1994; 9: 245–52CrossRefGoogle Scholar
Jenkins, CDStanton, BANiemcryk, SRose, RMA scale for the estimation of sleep problems in clinical research. J Clin Epidemiol 1988; 41: 313–21CrossRefGoogle ScholarPubMed
Johnson, LCSpinweber, CLQuality of sleep and performance in the Navy: a longitudinal study of good sleepers and poor sleepers. In: Guilleminault, CLugaresi, E ed. Sleep-wake Disorders: Natural History, Epidemiology, and Long Term Evolution New York: Raven Press, 1983 1318Google Scholar
Kelly, FDelahaye, CLe Gal, MQuality of life and insomnia. Results of the validation studies for a specifically designed questionnaire. JAMA SEA January 1993 21–6Google Scholar
Léger, DThe cost of sleep-related accidents: a report for the National Commission on Sleep Disorders Research. Sleep 1994; 17: 8493CrossRefGoogle ScholarPubMed
Mendelson, WBGarnett, DLinnoila, MDo insomniacs have impaired daytime functioning ?. Biol Psychiatry 1984; 19: 1261–63Google ScholarPubMed
Submit a response

Comments

No Comments have been published for this article.