Hostname: page-component-cd9895bd7-8ctnn Total loading time: 0 Render date: 2024-12-25T02:30:49.903Z Has data issue: false hasContentIssue false
  • English
  • Français

Sexual dysfunction: The unspoken side effect of antipsychotics

Published online by Cambridge University Press:  16 April 2020

J Peuskens ,
P Sienaert  and
M De Hert
J Peuskens
Affiliation:
Psychiatric Centre of the University St-Joseph, Leuvensesteenweg 51Z B-3070, Kortenberg, Belgium
P Sienaert
Affiliation:
Psychiatric Centre of the University St-Joseph, Leuvensesteenweg 51Z B-3070, Kortenberg, Belgium
M De Hert
Affiliation:
Psychiatric Centre of the University St-Joseph, Leuvensesteenweg 51Z B-3070, Kortenberg, Belgium
Get access

Summary

Although only a few studies have been performed and published data are scarce, it seems clear that sexual dysfunctions frequently occur during treatment with antipsychotics in 30–60% of patients with schizophrenia. It is important to evaluate the occurrence of sexual dysfunction and its relation to antipsychotic treatment.

Keywords

sexual dysfunctionschizophreniaantipsychotics
Type
Research Article
Information
European Psychiatry , Volume 13 , Issue S1 , 1998 , pp. 23s - 30s
Copyright
Copyright © Elsevier, Pari 1998

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Aizenberg, D, Zemishlany, Z, Dorfman-Entrol, P, Weizman, ASexual dysfunction in male schizophrenic patients J Clin Psychiatry 1995; 56: 137–141Google ScholarPubMed
Akhtar, S, Thomson, JASchizophrenia and sexuality: a review and a report of twelve unusual cases - Part II J Clin Psychiatry 1980; 41: 166–174Google Scholar
Arato, M, Erdos, A, Polgar, MEndocrinological changes in patients with sexual dysfunction under long-term antipsychotic treatment Pharmakopsychiatrie Neuropsychopharmakol 1979; 12: 426–431CrossRefGoogle Scholar
Barnes, TRE, Harvey, CAPsychiatric drugs and sexualityRiley, AJ, Peet, M, Wilson, CSexual Pharmacology Washington DC: Oxford Medical Publications, 1993 176–196Google Scholar
Berger, SHTrifluoperazine and haloperidol: sources of ejaculatory pain? Am J Psychiatry 1979; 136: 650Google ScholarPubMed
Cournos, F, Guido, JR, Coomaraswamy, S, Meyer-Bahlburg, H, Sugden, R, Horwath, ESexual activity and risk of HIV infection among patients with schizophrenia Am J Psychiatry 1994; 151: 228–232Google ScholarPubMed
Fañanás, L, Bertranpetit, JReproductive rates in families of schizophrenic patients in a case-control study Acta Psychiatr Scand 1995; 91: 202–204CrossRefGoogle ScholarPubMed
Finn, SE, Bailey, JM, Schultz, RT, Faber, RSubjective utility ratings of neuroleptics in treating schizophrenia Psychol Med 1990; 35: 843–848CrossRefGoogle Scholar
Fleischhacker, WW, Meise, U, Gunther, V, Kurz, MCompliance with antipsychotic drug treatment: influence of side effects Acta Psychiatr Scand 1994; 89: 11–15Google Scholar
Ghadirian, AM, Chouinard, G, Annable, LSexual dysfunction and plasma prolactin levels in neuroleptic-treated schizophrenic outpatients J Nerv Ment Dis 1982; 170: 463–467CrossRefGoogle ScholarPubMed
Gitlin, MJPsychotropic medications and their effects on sexual function: diagnosis, biology, and treatment approaches J Clin Psychiatry 1994; 55: 406–413Google ScholarPubMed
Hamner, M, Arvanitis, L, Miller, B, Link, C, Hong, WPlasma prolactin in schizophrenia subjects treated with Seroquel Psycopharmacol Bull 1996; 32: 107–110Google ScholarPubMed
Kaplan, HSThe new sex therapy Oxford: Penguin, 1974Google Scholar
Kelly, JA, Murphy, DA, Bahr, GR, Brasfield, TL, Davis, DR, Hauth, AC, et al.AIDS/HIV risk behaviour among the chronic mentally ill Am J Psychiatry 1992; 149: 886–889Google ScholarPubMed
Kotin, J, Wibert, DE, Verburg, D, Soldinger, SMThioridazine and sexual dysfunction Am J Psychiatry 1976; 133: 82–85Google ScholarPubMed
Lane, A, Byrne, M, Mulvaney, F, Kinsella, A, Waddington, JL, Walsh, D, et al.Reproductive behaviour in schizophrenia relative to other mental disorders: evidence for increased fertility in men despite decreased marital rate Acta Psychiatr Scand 1995; 91: 222–228CrossRefGoogle ScholarPubMed
Lingjaerde, O, Ahlfors, VG, Dencker, SJ, Elgen, KThe UKU side effect rating scale for psychotropic drugs and a cross sectional study of side effects in antipsychotic patients Acta Psychiatr Scand Suppl 1987; 334: 76Google Scholar
McKinnon, K, Cournos, F, Meyer Bahlburg, HFL, Guido, JR, Caraballo, LR, Margoshes, ES, et al.Reliability of sexual risk behaviour interviews with psychiatric patients Am J Psychiatry 1993; 150: 972–974Google ScholarPubMed
Meston, CM, Gorzalka, BBPsychoactive drugs and human sexual behaviour: the role of serotonergic activity J Psychoactive Drugs 1992; 24: 1–40CrossRefGoogle ScholarPubMed
Mitchell, JE, Popkin, MKAntipsychotic drug therapy and sexual dysfunction in men Am J Psychiatry 1982; 139: 633–637Google ScholarPubMed
Nestoros, JN, Lehmann, HE, Ban, TASexual behaviour of the male schizophrenic: the impact of illness and medications Arch Sex Behav 1981; 10: 421CrossRefGoogle ScholarPubMed
Peacock, L, Solgard, T, Lublin, H, Gerlach, JClozapine verses typical antipsychotics: effects and side effects Neuropsychopharm 1994; 10: 228–354Google Scholar
Peuskens, JRisperidone in the treatment of patients with chronic schizophrenia: a multinational, multicentre, double-blind, parallel group study versus haloperidol Brit J Psychiatry 1995; 166: 712–726CrossRefGoogle Scholar
Pfeiffer, W, Kockott, G, Fischl, B, Schleuning, GUnerwünschte Wirkungen psychopharmakologischer Langzeittherapie auf die sexuellen Funktionen Psychiatr Prax 1991; 18: 92–98Google Scholar
Pollack, MH, Reiter, S, Hammerness, PGenitourinary and sexual adverse effects of psychotropic medication Int J Psychiatry in Medicine 1992; 22: 305–327CrossRefGoogle ScholarPubMed
Riley, AJAlpha adrenoceptors and human sexual functionBancroft, JThe Pharmacology of Sexual Function and Dysfunction Hamondsworth: Elsevier Science BV, 1995 307–322Google Scholar
Schiavi, RC, Segraves, RTThe biology of sexual function Psychiatr Clin North Am 1995; 18: 7–23CrossRefGoogle ScholarPubMed
Schiavi, RC, Segraves, RTThe biology of sexual function Psychiatr Clin North Am 1995; 18: 7–23CrossRefGoogle ScholarPubMed
Segraves, RTEffects of psychotropic drugs on human erection and ejaculation Arch Gen Psychiatry 1989; 46: 275–284CrossRefGoogle ScholarPubMed
Strauss, B, Gross, JPsychopharmakabedingte Veränderungen der Sexualität ( Häufigkeit und Stellenwert in der psychiatrischen Praxis Psychiatr Prax 1984; 11: 49–55Google Scholar
Sullivan, G, Lukoff, DSexual side effects of antipsychotic medication: evaluation and interventions Hosp Community Psychiatry 1990; 41: 1238–1241Google ScholarPubMed
Susser, E, Valacnia, E, Miller, M, Tsai, WY, Meyer-Bahlburg, H, Conover, SSexual behaviour of homeless mentally ill men at risk for HIV Am J Psychiatry 1995; 152: 583–587Google ScholarPubMed
Verhulst, J, Schneidman, BSchizophrenia and Sexual Functioning Hosp Community Psychiatry 1981; 32: 259–262Google ScholarPubMed
Wilson, CAPharmacological targets for the control of male and female sexual behaviourRiley, AJ, Peet, M, Wilson, CSexual Pharmacology Amsterdam: Oxford Medical Publications, 1993 1–58Google Scholar
Submit a response

Comments

No Comments have been published for this article.