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Quality of life and treatment costs in schizophrenic outpatients, treated with depot neuroleptics

Published online by Cambridge University Press:  16 April 2020

M.Z. Dernovsek ,
V. Prevolnik Rupel ,
M. Rebolj  and
R. Tavcar
M.Z. Dernovsek*
Affiliation:
University Psychiatric Hospital, Studenec 48, SI-1260Ljubljana-Polje, Slovenia
V. Prevolnik Rupel
Affiliation:
Ministry of Health, Stefanova 5, SI-1000Ljubljana, Slovenia
M. Rebolj
Affiliation:
School of Economics, Kardeljeva ploscad 17, SI-1000Ljubljana, Slovenia
R. Tavcar
Affiliation:
University Psychiatric Hospital, Studenec 48, SI-1260Ljubljana-Polje, Slovenia
*
*Correspondence and reprints. E-mail address:[email protected] (M.Z. Dernovsek).
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Summary

Study aim was 1) to find out the influences on quality of life (QoL) of chronic outpatients with schizophrenia; 2) to calculate Quality Adjusted Life Years (QALY); and 3) to estimate direct 1-year treatment costs. In a 20% sample (100 males, 100 females) of schizophrenic outpatients from the Outpatients Clinic in Ljubljana, Slovenia receiving depot neuroleptics demographic, clinical, and treatment data were collected for the year 1996. The Krawiecka Scale, Global Assessment Scale (GAS), Abnormal Involuntary Movement Scale, Rating Scale for Drug-Induced Akathisia, Rating Scale for Extrapyramidal Side Effects, Quality of Life Scale (QLS), EQ-5D and QALY were used. Multivariate linear regression was used with the QLS score as dependent variable. The patients were on average 44 years old and had been treated for 14 years. The average GAS score was 70. GAS was positively related to the QLS score while the parkinsonism score was inversely correlated with QLS. The patients can expect to live for 10. 20 more QALY on average. The QoL on the EQ-5D scale was 0.73. The annual direct treatment costs amounted to $216,216 in 1996 prices. In well-adjusted chronic patients with schizophrenia the QoL seems to depend mostly on their psychosocial performance and side effects. Although rare, rehospitalisations accounted for one-half of all treatment expenses.

Keywords

outpatientsquality of liferehospitalisationschizophrenia
Type
Original Articles
Information
European Psychiatry , Volume 16 , Issue 8 , December 2001 , pp. 474 - 482
Copyright
Copyright © 2001 Éditions scientifiques et médicales Elsevier SAS

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