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Psoriasis and psychiatric disorders

Published online by Cambridge University Press:  13 August 2021

H. Ghabi ,
A. Aissa ,
S. Meddouri ,
U. Ouali  and
F. Nacef
H. Ghabi
Affiliation:
Psychiatry A, Razi Hospital, Manouba, Tunisia
A. Aissa*
Affiliation:
Psychiatry A, Razi Hospital, Manouba, Tunisia
S. Meddouri
Affiliation:
Psychiatry A, Razi Hospital, Manouba, Tunisia
U. Ouali
Affiliation:
Psychiatry A, Razi Hospital, Manouba, Tunisia
F. Nacef
Affiliation:
Psychiatry A, Razi Hospital, Manouba, Tunisia
*
*Corresponding author.

Abstract

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Introduction

Psoriasis is a common psychophysiological chronic skin disease with an important impact on patient’s quality of life. The prevalence of psychiatric conditions in psoriasis may range from 24% to 90%. The mechanisms that may explain this relationship still remain debatable.

Objectives

The purpose of this work was to report two cases of psychiatric comorbidities associated with psoriasis and to discuss the possible etiopathogenic mechanisms behind this connection.

Methods

To report two cases of psychiatric comorbidities associated with psoriasis.

Results

Case1 Mr. A.K. is a 30-year-old male patient. He was admitted to our department in February 2020 for acute mania with psychotics features.the patient reported that since 2010, he was treated for psoriasis with local treatment (cortisone cream). The lesions did not grow or expand. Case2 Mr.A.B.is a 27-year-old male patient, with past history of psoriasis under local treatment. He is treated since 2019 in our department for schizophrenia.

Conclusions

High levels of pro-inflammatory cytokines observed in psoriasis may in part explain the associated psychiatric disorders. The psychodermatologic approach would be beneficial for the adequate management of patients suffering from psoriasis.

Disclosure

No significant relationships.

Keywords

psoriasisPsychiatric comorbidities
Type
Abstract
Information
European Psychiatry , Volume 64 , Special Issue S1: Abstracts of the 29th European Congress of Psychiatry , April 2021 , pp. S646
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of the European Psychiatric Association
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