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Proton magnetic resonance spectroscopy (1H-MRS) of the thalamus in schizophrenia

Published online by Cambridge University Press:  16 April 2020

P Delamillieure ,
J.M Constans ,
J Fernandez ,
P Brazo  and
S Dollfus
P Delamillieure
Affiliation:
Groupe d’Imagerie Neurofonctionnelle UMR CNRS 6095/CEA/Université de Caen et Paris V et Centre Esquirol, Centre Hospitalier et Universitaire, 14000Caen, France
J.M Constans
Affiliation:
Centre IRM, Centre Hospitalier et Universitaire, 14000Caen, France
J Fernandez
Affiliation:
Centre IRM, Centre Hospitalier et Universitaire, 14000Caen, France
P Brazo
Affiliation:
Groupe d’Imagerie Neurofonctionnelle UMR CNRS 6095/CEA/Université de Caen et Paris V et Centre Esquirol, Centre Hospitalier et Universitaire, 14000Caen, France
S Dollfus*
Affiliation:
Groupe d’Imagerie Neurofonctionnelle UMR CNRS 6095/CEA/Université de Caen et Paris V et Centre Esquirol, Centre Hospitalier et Universitaire, 14000Caen, France
*
*Correspondence and reprints. Email address: [email protected] (S. Dollfus).
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Extract

This study applied 1H-MRS in the thalamus of schizophrenic patients and healthy subjects.

There were no differences in the metabolite ratios (NAA/Cr, Cho/Cr or mI/Cr) between the two groups. Relationships were noted between NAA/Cr and age in patients with a trend toward this correlation in controls, suggesting an effect of age on the metabolism of the thalamus.

Keywords

agingN-acetyl-aspartateschizophreniaspectroscopythalamus
Type
Short Communication
Information
European Psychiatry , Volume 15 , Issue 8 , December 2000 , pp. 489 - 491
Copyright
Copyright © 2001 Éditions scientifiques et médicales Elsevier SAS. All rights reserved

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