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Predictors of Remission at 1-year Follow-up among ocd Patients: Findings from The Netherlands Obsessive-compulsive Disorder Association (NOCDA) Study

Published online by Cambridge University Press:  23 March 2020

L. Tibi ,
P. van Oppen ,
A. van Balkom ,
M. Eikelenboom  and
G. Anholt
L. Tibi
Affiliation:
Ben Gurion University, Psychology, Be’er Sheva, Israel
P. van Oppen
Affiliation:
VU University Medical Center, Psychiatry, Amsterdam, The Netherlands
A. van Balkom
Affiliation:
VU University Medical Center, Psychiatry, Amsterdam, The Netherlands
M. Eikelenboom
Affiliation:
VU University Medical Center, Psychiatry, Amsterdam, The Netherlands
G. Anholt
Affiliation:
Ben Gurion University, Psychology, Be’er Sheva, Israel

Abstract

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Introduction

Obsessive-compulsive disorder (OCD) is described as a chronic condition. However, relatively little is known about predictors affecting its long-term outcome.

Objective

To examine the contribution of clinical and interpersonal determinants in predicting remission status of 254 OCD patients at one-year follow-up (FU1).

Methods

We used the baseline and FU1 data of The Netherlands obsessive-compulsive disorder association (NOCDA) study. Clinical predictors were chronicity level, depressive and obsessive-compulsive symptom severity. Suspected interpersonal factors included attachment style, social support and expressed emotion. Remission status was defined using the Yale-Brown obsessive-compulsive symptom (Y-BOCS) scale. χ2 tests and ANOVAs were used for bivariate analyses, followed by multivariate multinomial logistic regression analyses to assess main effects and interactions in predicting remission status at FU1.

Results

Bivariate tests demonstrated significant differences in remission status as a function of chronicity level, depressive and obsessive-compulsive symptom severity and social support. Regression analyses revealed that increased baseline OCD severity reduced the odds for both partial and full remission at FU1 (OR = .87, 95%CI = .82–93, P < 0.001). Increased depressive severity at baseline reduced the odds for partial remission at FU1 (OR = .95, 95%CI = .91–.98, P < 0.01). Interactions analyses demonstrated that the adverse effects of OCD severity on partial remission disappeared at the presence of secure attachment (IOR = 1.11, 95%CI = 1.05–1.24, P < 0.05) and high social support (IOR = .88, 95%CI = .78–98, P < 0.05).

Conclusions

The contribution of clinical severity is critical for understanding the prognosis of OCD. The interpersonal context of OCD patients may mitigate the unfavorable effect of severity on outcome, thus should be addressed in treatment.

Disclosure of interest

The authors have not supplied their declaration of competing interest.

Type
Oral communications: Anxiety disorders and somatoform disorders; depression; obsessive-compulsive disorder and personality and personality disorders
Information
European Psychiatry , Volume 41 , Issue S1: Abstract of the 25th European Congress of Psychiatry , April 2017 , pp. S73
Copyright
Copyright © European Psychiatric Association 2017
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