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Pharmacotherapeutic response of DST-positive borderline patients

Published online by Cambridge University Press:  16 April 2020

VP Kontaxakis
Affiliation:
Department of Psychiatry, University of Athens, Eginition Hospital, 74 Vas. Sophias Avenue, 11528Athens, Greece
M Markianos
Affiliation:
Department of Psychiatry, University of Athens, Eginition Hospital, 74 Vas. Sophias Avenue, 11528Athens, Greece
C Stefanis
Affiliation:
Department of Psychiatry, University of Athens, Eginition Hospital, 74 Vas. Sophias Avenue, 11528Athens, Greece
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Summary

The cases of two borderline patients are presented, dexamethasone suppression test (DST) positive and refractory to many therapeutic interventions and treated successfully with high doses of amitriptyline (225 and 200 mg/day, respectively). During the therapeutic intervention, the psychopathological condition of the patients was evaluated using Hamilton's rating scale for depression and a constructed scale based on items 11, 12 and 13 (dysphoria, anger, sense of emptiness, boredom, anhedonia) of the diagnostic interview for borderline patients.

Type
Short communication
Copyright
Copyright © Elsevier, Paris 1995

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