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Paroxysmal MEG activity in obsessive compulsive patients without SSRIs therapy

Published online by Cambridge University Press:  16 April 2020

C. Amo ,
A. Fernández ,
J.M. León ,
T. Ortiz ,
F. Maestú ,
F. Ferre ,
M.I. López-Ibor  and
J.J. López-Ibor
C. Amo
Affiliation:
Magnetoencephalography Center “Dr Pérez Modrego”, Faculty of Medicine (Pabellón 8), Universidad Complutense de Madrid, Avenida Complutense s/n, 28040Madrid, Spain
A. Fernández
Affiliation:
Magnetoencephalography Center “Dr Pérez Modrego”, Faculty of Medicine (Pabellón 8), Universidad Complutense de Madrid, Avenida Complutense s/n, 28040Madrid, Spain Department of Psychiatry, Faculty of Medicine, Universidad Complutense de Madrid, Spain
J.M. León
Affiliation:
Department of Clinical Neurophysiology, Hospital Ramón y Cajal, Madrid, Spain
T. Ortiz*
Affiliation:
Magnetoencephalography Center “Dr Pérez Modrego”, Faculty of Medicine (Pabellón 8), Universidad Complutense de Madrid, Avenida Complutense s/n, 28040Madrid, Spain Department of Psychiatry, Faculty of Medicine, Universidad Complutense de Madrid, Spain
F. Maestú
Affiliation:
Magnetoencephalography Center “Dr Pérez Modrego”, Faculty of Medicine (Pabellón 8), Universidad Complutense de Madrid, Avenida Complutense s/n, 28040Madrid, Spain
F. Ferre
Affiliation:
Department of Psychiatry, Faculty of Medicine, Universidad Complutense de Madrid, Spain
M.I. López-Ibor
Affiliation:
Department of Psychiatry, Faculty of Medicine, Universidad Complutense de Madrid, Spain Department of Psychiatry, Hospital Clínico Universitario San Carlos, Madrid, Spain
J.J. López-Ibor
Affiliation:
Department of Psychiatry, Faculty of Medicine, Universidad Complutense de Madrid, Spain Department of Psychiatry, Hospital Clínico Universitario San Carlos, Madrid, Spain
*
*Corresponding author. E-mail address:[email protected] (T. Ortiz).
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Abstract

We describe a fronto-temporal paroxysmal rhythmic activity registered by magnetoencephalography (MEG) in two patients with obsessive compulsive disorder (OCD) without SSRIs treatment. The localization of the activity involves cingulate cortex and frontal areas. We think that these MEG findings are related to the disease itself, rather than representing pharmacological SSRIs effect.

Keywords

MagnetoencephalographyObsessive compulsive disorderParoxysmal activitySSRIs
Type
Short communication
Information
European Psychiatry , Volume 21 , Issue 2 , March 2006 , pp. 139 - 141
Copyright
Copyright © Elsevier SAS 2006

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