Hostname: page-component-586b7cd67f-dsjbd Total loading time: 0 Render date: 2024-11-24T08:48:40.974Z Has data issue: false hasContentIssue false
  • English
  • Français

P300 event-related brain potential and personality in depression

Published online by Cambridge University Press:  16 April 2020

M. Hansenne ,
W. Pitchot ,
E. Pinto ,
J Reggers ,
P. Papart  and
M. Ansseau
M. Hansenne*
Affiliation:
Department of Psychiatry, Centre Hospitalier Universitaire du Sart Tilman (B-35), B-4000Liège, Belgium
W. Pitchot
Affiliation:
Department of Psychiatry, Centre Hospitalier Universitaire du Sart Tilman (B-35), B-4000Liège, Belgium
E. Pinto
Affiliation:
Department of Psychiatry, Centre Hospitalier Universitaire du Sart Tilman (B-35), B-4000Liège, Belgium
J Reggers
Affiliation:
Department of Psychiatry, Centre Hospitalier Universitaire du Sart Tilman (B-35), B-4000Liège, Belgium
P. Papart
Affiliation:
Department of Psychiatry, Centre Hospitalier Universitaire du Sart Tilman (B-35), B-4000Liège, Belgium
M. Ansseau
Affiliation:
Department of Psychiatry, Centre Hospitalier Universitaire du Sart Tilman (B-35), B-4000Liège, Belgium
*
*Correspondence and reprints
Get access

Summary

P300 is an event-related brain potential (ERP) particularly interesting to the study of cognitive processes in normal subjects and in psychopathology. P300 has been applied in depression with controversial results. A major source for these controversial results could result from the diversity of depressed patients included in the different studies. Supporting this assumption, impulsivity, blunted affect, suicidal behavior and psychotic features significantly influence P300 amplitude. However, no data are available on the possible influences of the personality of depressed patients on P300. Since personality is related to P300 in normal subjects, the aim of the present study is to investigate the relationship between ERPs (P200, N200, and P300) and the Temperament and Character Inventory (TCI) in 54 depressed patients. The main results of the study concern the absence of major correlations between personality dimensions as assessed by the TCI and ERP parameters among depressed patients. Only weak partial positive correlations relate N200 latency with harm avoidance, and P300 amplitude (Pz) with the self-directedness dimension. N200 amplitude is also negatively correlated to persistence. However, the preliminary nature of the presented results with respect to the weak statistical significance should be underlined.

Keywords

N200P200P300depressionpersonalityTCI
Type
Original article
Information
European Psychiatry , Volume 15 , Issue 6 , September 2000 , pp. 370 - 377
Copyright
Copyright © Éditions scientifiques et médicales Elsevier SAS 2000

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Alexander, J.E, Polich, JP300 differences between sinistrals and dextrals Cogn Brain Res 2 1995 277–282CrossRefGoogle ScholarPubMed
Akiskal, H.S, Hirschfield, R, Yerevanian, BThe relationship of personality to affective disorders Arch Gen Psychiatry 40 1983 801–810CrossRefGoogle ScholarPubMed
American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th ed. Washington 1994 DC: American Psychiatric AssociationGoogle Scholar
Bayon, C, Hill, K, Svrakic, D.M, Przybeck, T.R, Cloninger, C.RDimensional assessment of personality in an out-patients sample: relations of the systems of Millon and Cloninger J Psychiatr Res 30 1996 341–352CrossRefGoogle Scholar
Black, K.J, Sheline, Y.LPersonality disorder scores improve with effective pharmacotherapy of depression J Aff Disord 43 1997 11–18CrossRefGoogle ScholarPubMed
Brown, S.L, Svrakic, D.M, Przybeck, T.R, Cloninger, C.RThe relationship of personality to mood and anxiety states: a dimensional approach J Psychiatr Res 26 1992 197–211CrossRefGoogle ScholarPubMed
Bruder, G.E, Towey, J.P, Stewart, J.W, Friedman, D, Tenke, C, Quitkin, F.MEvent-related potentials in depression: influence of task, stimulus hemifield and clinical features on P3 latency Biol Psychiatry 30 1991 233–246CrossRefGoogle ScholarPubMed
Cahill, J.M, Polich, JP300, probability, and introverted/extroverted personality types Biol Psychol 33 1992 23–35CrossRefGoogle ScholarPubMed
Charney, D.S, Nelson, J.C, Quinlan, D.MPersonality traits and disorder in depression Am J Psychiatry 138 1981 1601–1604Google ScholarPubMed
Chien, A.J, Dunner, D.LThe tridimensional personality questionnaire in depression: state versus trait issues J Psychiatr Res 30 1996 21–27CrossRefGoogle ScholarPubMed
Cloninger, C.RA unified biosocial theory of personality and its role in the development of anxiety states Psychiatr Dev 3 1986 167–226Google Scholar
Cloninger, C.R, Svrakic, D.MIntegrative psychobiological approach to psychiatric assessment and treatment Psychiatry 60 1997 120–141CrossRefGoogle ScholarPubMed
Cloninger, C.R, Svrakic, D.M, Przybeck, T.RA psychobiological model of temperament and character Arch Gen Psychiat 50 1993 975–990CrossRefGoogle ScholarPubMed
Cloninger, C.R, Przybeck, T.R, Svrakic, D.M, Wetzel, R.DThe Temperament and Character Inventory (TCI): a guide to its development and use. Center for psychobiology of personality 1994 Washington University St Louis, MissouriGoogle Scholar
Daruna, J.H, Karrer, R, Rosen, A.JIntroversion, attention and the late positive component of event-related potentials Biol Psychol 20 1985 249–259CrossRefGoogle ScholarPubMed
Desmedt, J.EP300 in serial tasks: an essential post-decision closure mechanism Progr Brain Res 54 1981 682–686CrossRefGoogle Scholar
Diner, C.B, Holcomb, P.J, Dykman, R.AP300 in major depressive disorder Psychiatry Res 15 1985 175–184CrossRefGoogle ScholarPubMed
DiTraglia, G, Polich, JP300 and introverted/extraverted personality types Psychophysiol 28 1991 177–184CrossRefGoogle ScholarPubMed
Donchin, ESurprise . . .surprise? Psychophysiol 18 1981 493–513CrossRefGoogle ScholarPubMed
Donchin, E, Coles, M.HG. Is the P300 component a manifestation of context updating? Brain Behav Sci 11 1988 357–374CrossRefGoogle Scholar
El Massioui, F, Lesèvre, NAttention impairment and psychomotor retardation in depressed patients: an event–related study Electroencephal Clin Neurophysiol 70 1988 46–55CrossRefGoogle Scholar
Eysenck, H.JBiological bases of personalityPervin, L.AHandbook of personality. Theory and research. 1990 Guilford Press New York244–276Google Scholar
Gangadhar, B.N, Ancy, J, Janakiramaiah, N, Umapathy, CP300 amplitude in non-bipolar, melancholic depression J Aff Disord 28 1993 57–60CrossRefGoogle ScholarPubMed
Giedke, H, Bolz, J, Heimann, HEvoked potentials, expectancy wave and skin resistance in depressed patients and healthy controls PharmakoPsychiatr 13 1980 91–101CrossRefGoogle ScholarPubMed
Gordon, E, Kraiuhin, C, Harris, A, Meares, R, Howson, AThe differential diagnosis of dementia using P300 latency Biol Psychiatry 21 1986 1123–1132CrossRefGoogle ScholarPubMed
Hamilton, MA rating scale of depression J Neurol Neurosurg Psychiatry 23 1960 56–62CrossRefGoogle Scholar
Hansenne, MP300 and personality: an investigation with the Cloninger model of personality Biol Psychol 50 1999 143–155CrossRefGoogle ScholarPubMed
Hansenne, M, Pitchot, W, Gonzalez Moreno, A, Gonzalez Torrecilas, J, Mirel, J, Ansseau, MPsychophysiological correlates of suicidal behavior in depression A preliminary study. Neuropsychobiology 30 1994 1–3CrossRefGoogle ScholarPubMed
Hansenne, M, Pitchot, W, Gonzalez Moreno, A, Urcelay Zaldua, I, Ansseau, MSuicidal behavior in depressive disorder: an event-related potential study Biol Psychiatry 40 1996 116–122CrossRefGoogle Scholar
Hansenne, M, Pitchot, W, Gonzalez Moreno, A, Reggers, J, Machurot, P.Y, Ansseau, MHarm avoidance dimension of the tridimensional personality questionnaire (TPQ) and serotonin-1A activity in depressed patients Biol Psychiatry 10 1997 959–961CrossRefGoogle Scholar
Hansenne, M, Pitchot, W, Gonzalez Moreno, A, Machurot, P.Y, Ansseau, MThe tridimensional personality questionnaire and depression Eur Psychiatry 13 1988 101–103CrossRefGoogle Scholar
Hansenne, M, Pitchot, W, Pinto, E, Kjiri, K, Ajamieh, A, Ansseau, MTemperament and character inventory (TCI) and depression J Psychiatr Res 33 1999 31–36CrossRefGoogle ScholarPubMed
Have, G, Kolbeinson, H, Pétursson, HDementia and depression in old age: psychophysiological aspects Acta Psychiatr Scand 83 1991 329–333CrossRefGoogle ScholarPubMed
Hirschfeld, R.M.A, Klerman, G.L, Clayton, P.J, Keller, M.B, McDonald-Scott, P, Larkin, BAssessing personality: effects of the depressive state on trait measurement Am J Psychiatry 140 1983 695–699Google ScholarPubMed
Hirschfeld, R.M.A, Shea, M.T, Holzer, C.EPersonality dysfunction and depressionHoning, A, van Praag, H.MDepression: neurobiological, psychopathological and therapeutic advances. 1997 John Wiley New York327–341Google Scholar
Joffe, R.T, Regan, J.JPersonality and depression J Psychiat Res 22 1988 279–286CrossRefGoogle ScholarPubMed
Joffe, R.T, Bagby, R.M, Levitt, A.J, Regan, J.J, Parker, J.DA. The tridimensional personality questionnaire in major depression Am J Psychiatry 150 1993 959–960Google ScholarPubMed
Johnson, RA triarchic model of P300 amplitude Psychophysiol 23 1986 367–384CrossRefGoogle ScholarPubMed
Johnson, ROn the neural generators of the P300 component of the event-related potential Psychophysiol 30 1993 90–97CrossRefGoogle Scholar
Kok, AInternal and external control: a two-factor model of amplitude change of event-related potentials Acta Psychologica 74 1990 203–236CrossRefGoogle ScholarPubMed
Kutas, M, McCarthy, G, Donchin, EAugmenting mental chronometry: the P300 as a measure of stimulus evaluation time Science 197 1977 792–795CrossRefGoogle ScholarPubMed
Lembreghts, M, Crasson, M, El Ahmadi, A, Timsit-Berthier, MEtude de la variabilité interindividuelle des potentiels évoqués auditifs exogènes et endogènes en condition d’attention volontaire Neurophysiol Clin/Clin Neurophysiol 25 1995 203–223CrossRefGoogle Scholar
Lépine, J.P, Pélissolo, A, Téodorescu, R, Téhérani, MEvaluation des propriétés psychométriques de la version française du questionnaire tridimensionel de la personnalité (TPQ) Encéphale XX 1994 747–753Google Scholar
McCarthy, G, Donchin, EA metric for thought: a comparison of P300 latency and reaction time Science 211 1981 77–80CrossRefGoogle ScholarPubMed
Mulder, GThe concept and measurement of mental effortHockey, R.J, Gaillard, A.W.K, Coles, M.H.GEnergetic and human information processing. 1986 Martinus Nijhoff Dordecht175–198CrossRefGoogle Scholar
Mulder, R.T, Joyce, P.R, Cloninger, C.RTemperament and early environment influence comorbidity and personality disorders in major depression Comp Psychiatry 35 1994 225–233CrossRefGoogle ScholarPubMed
Muir, W.J, St Clair, D.M, Blackwood, D.H.RLong-latency auditory event-related potentials in schizophrenia and in bipolar and unipolar affective disorder Psychol M 21 1991 867–879CrossRefGoogle ScholarPubMed
Nelson, E.C, Cloninger, C.RThe Tridimensional questionnaire as a predictor of response to nefazodone treatment of depression J Aff Disord 35 1995 51–57CrossRefGoogle ScholarPubMed
O’Connor, K.PIndividual differences in components of slow cortical potentials: implications for models of information processing Pers Ind Diff 4 1983 403–410CrossRefGoogle Scholar
Patterson, J.V, Mikaleski, H.J, Starr, ALatency variability of the components of auditory event related potentials to infrequent stimuli in aging, Alzheimer type dementia and depression Electroencephal Clin Neurophysiol 71 1988 450–460CrossRefGoogle ScholarPubMed
Pélissolo, A, Lépine, J.PTraduction française et premières études de validation du questionnaire de personnalité TCI Ann Méd-Psychol 155 1997 497–508Google Scholar
Picton, T.WThe P300 wave of the human event-related potential J Clin Neurophysiol 9 1992 456–479CrossRefGoogle ScholarPubMed
Pierson, A, Partiot, A, Ammar, S, Dodin, V, Loas, G, Jouvent, R et al. ERP differences between anxious-impulsive and blunted-affect depressive inpatientsAnsseau, M, von Frenckell, R, Frank, GBiological markers of depression: state of the art. 1991 Elsevier Science Amsterdam121–129Google Scholar
Pierson, A, Partiot, A, Jouvent, R, Bungener, C, Martinerie, J, Renault, B et al. Loss of control of pre-motor activation in anxious agitated and impulsive depressives. A clinical and ERP study Prog Neuro-Psychopharmacol Biol Psychiatry 18 1994 1037–1050CrossRefGoogle ScholarPubMed
Pierson, A, Ragot, R, Martinerie, J, Partiot, A, Renault, B, Jouvent, RHeterogeneity of information-processing alterations according to dimensions of depression: an event-related potentials study Biol Psychiatry 40 1996 98–115CrossRefGoogle Scholar
Plooij-Van Gorsel, EEvoked potential correlates of information processing and habituation in depressive illness Ann New York Acad Sc 425 1984 609–617CrossRefGoogle ScholarPubMed
Polich, J, Martin, SP300, cognitive capability, and personality: a correlational study of university undergrades Pers Ind Diff 13 1992 533–543CrossRefGoogle Scholar
Reich, J, Noyes, R, Hirschfeld, R, Coryell, W, O’Gorman, TState and personality in depressed and panic patients Am J Psychiatry 144 1987 181–187Google ScholarPubMed
Rogers, T.D, Deary, IThe P300 component of the auditory event-related potential in monozygotic and dizygotic twins Acta Psychiatr Scand 83 1991 412–416CrossRefGoogle ScholarPubMed
Sanderson, W.C, Wetzel, S, Beck, A.TPrevalence of personality disorders in patients with major depressive and dysthymia Psychiatry Res 42 1992 93–99CrossRefGoogle ScholarPubMed
Santosh, P.J, Malhotra, S, Raghunathan, M, Mehra, Y.NA study of P300 in melancholic depression. Correlation with psychotic features Biol Psychiatry 35 1994 474–479CrossRefGoogle ScholarPubMed
Smulders, F.T.Y, Kok, A, Kenemans, J.L, Bashore, T.RThe temporal selectivity of additive factor effects on the reaction process revealed in ERP component latencies Acta Psychologica 90 1995 97–109CrossRefGoogle ScholarPubMed
Sommer, W, Matt, JAwareness of P300-related cognitive processes: a signal detection approach Psychophysiol 27 1990 575–585CrossRefGoogle ScholarPubMed
Strakowski, S.M, Faedda, G.L, Tohen, M, Goodwin, D.C, Stoll, A.LPossible affective-state dependence of the tridimensional personality questionnaire in first-episode psychosis Psychiatry Res 41 1992 215–226CrossRefGoogle ScholarPubMed
Strakowski, S.M, Dunayevich, E, Keck, P.E, McElroy, S.LAffective state of the tridimensional questionnaire J Aff Disord 57 1995 209–214Google ScholarPubMed
Svrakic, D.M, Whitehead, C, Przybeck, T.R, Cloninger, C.RDifferential diagnosis of personality disorders by the seven-factor model of temperament and character Arch Gen Psychiatry 50 1993 991–999CrossRefGoogle Scholar
Verleger, REvent-related potentials and cognition: a critique of the context updating hypothesis and an alternative interpretation of P3 Behav Brain Sci 11 1988 343–356CrossRefGoogle Scholar
Verleger, R, Neukater, W, Kompf, D, Vieregesse, POn the reasons for the delay of P300 latency in healthy elderly subjects Electroencephalogr Clin Neurophysiol 79 1991 488–502CrossRefGoogle Scholar
Wetzel, R.D, Brown, S.L, Horn, C.J, Knesevich, M.A, Wolff, H, Cloninger, C.RCorrelates of tridimensional personality questionnaire scales with selected Minnesota multiphasic personality inventory scales Psychol Rep 71 1992 1027–1038CrossRefGoogle ScholarPubMed
Submit a response

Comments

No Comments have been published for this article.