P-1236 - Association Between Social Functioning, Quality of Life and Recovery Status in Schizophrenic Patients - a Longitudinal, Naturalistic Study

Abstract

Introduction

Symptomatic remission is an important outcome of schizophrenia however its association with social functioning (SF) and quality of life (QoL) hasn't been fully recognized.

Objectives

To assess SF and QoL in association with remission status according to Andreasen criteria.

Methods

This was a study of a group 64 patients hospitalized for the first time between 1998 - 2002. They were assessed 1 month following discharge (T. 1), 12 months later (T. 2), 4 – 6 years after T.1 (T. 3) and 7–11 years after T.1 (T. 4).

Results

During the observation 17.2% were remitted (Group 1), 37.5% were remitted or non remitted (Group 2), and 45.3% were non remitted (Group 3). There were differences between the groups however SFS and QL didn't change.

Remission status	Time 1 (mean)	Time 2 (mean)	Time 3 (mean)	Time 4 (mean)	P value
Group 1 recovered n=11
SFS	114.1	112.1	118.6	119.5	0.08
WHOQOL	92.7	92.4	94.4	93.9	0.99
Group 2 recovered/non-recovered n=24
SFS	103.9	105.4	110.5	111.2	0.18
WHOQOL	85.9	85.4	88.4	86.9	0.42
Group 3 non-recovered n=29
SFS	98.6	99.2	99.6	100.4	0.61
WHOQOL	77.8	78.7	75.6	77.1	0.96

[Table Social functioning and QoL]

Conclusion

Close association between remission status and SF and QoL suggests that remission status may be a good indicator for SF and QoL in schizophrenia.