Hostname: page-component-cd9895bd7-dk4vv Total loading time: 0 Render date: 2024-12-21T07:46:05.998Z Has data issue: false hasContentIssue false

P03-149 - Study on the Executive Function and Learning Ability of the First-Episode Schizophrenia

Published online by Cambridge University Press:  17 April 2020

H. Wang
Affiliation:
Psychiatry Department, Renmin Hospital of Wuhan University, Wuhan, China
X. Liu
Affiliation:
Psychiatry Department, Renmin Hospital of Wuhan University, Wuhan, China
Y. Fang
Affiliation:
Psychiatry Department, Renmin Hospital of Wuhan University, Wuhan, China

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Objectives

To investigate the executive function and learning ability of the patients with first-episode schizophrenia, and its relationship with the patients’ clinical symptoms.

Methods

50 schizophrenia patients and 50 healthy controls were tested by the Tower of London (TOL). All the subjects received two phases of the test of TOL continuously, with a break of 1 minute. And Positive and Negative Symptom Scale (PANSS) was used to assess the clinical symptoms of the patients.

Results

Compared with the control group, the number of reply during the 1st phase (x1) and the 2nd phase (x2)of the patients group, was lower (P<0.01); the reaction time during the 1st phase (t1) and the 2nd phase (t2) was longer (P<0.01); while the rate of correct answer during the 1st phase (p1) and the 2nd phase (p2) do not differ. For the control group, x2 was higher than x1 (P<0.01), and t2 was shorter than t1 (P<0.01). However, for the schizophrenia group, there were no difference between x1 and x2, t1 and t2. The value of x1, p1, x2 of the patients were correlated negatively with the PANSS negative subscale score (P< 0.05), and t1 and t2 were correlated positively with the the negative subscale score (P< 0.01). The performance of the TOL did not correlated with the PANSS positive subscale score and general psychopathology subscale score.

Conclusion

The executive function and learning ability of the schizophrenics are impaired and the impairment of the cognitive function is significantly correlated with the negative symptoms of schizophrenia patients.

Type
Psychotic disorders / Schizophrenia
Copyright
Copyright © European Psychiatric Association 2010
Submit a response

Comments

No Comments have been published for this article.