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P03-138 - Training Working Memory in Schizophrenia

Published online by Cambridge University Press:  17 April 2020

I.-K. Penner ,
M. Hubacher ,
A. Vogt ,
P. Calabrese ,
M. Weiland ,
K. Opwis  and
G. Stoppe
I.-K. Penner
Affiliation:
University of Basel, Basel, Switzerland
M. Hubacher
Affiliation:
Department of Cognitive Psychology, Basel, Switzerland
A. Vogt
Affiliation:
Department of Cognitive Psychology, Basel, Switzerland
P. Calabrese
Affiliation:
Department of Cognitive Psychology, Basel, Switzerland
M. Weiland
Affiliation:
Psychiatric University Hospitals, University of Basel, Basel, Switzerland
K. Opwis
Affiliation:
Department of Cognitive Psychology, Basel, Switzerland
G. Stoppe
Affiliation:
University Psychiatric Hospitals, Basel, Switzerland

Abstract

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Background

Cognitive deficits in schizophrenia consist of deficits in attention, concentration, fluency, and executive function. Especially the working memory deficits influence everyday function and rehabilitation.

Objective

The ame of the study was to investigate a potential of a neurocognitive intervention in schizophrenia (CS) and multiple sclerosis (MS) by application of a computerised working memory training.

Methods

So far, 30 ms patients and 14 cs patients were investigated. Patients are allocated to a treatment group or to a control design. At baseline, all participants underwent a comprehensive neuropsychological examination including memory, working memory, attention, concentration, information processing speed, mental flexibility and intelligence. The treatment group performed a computer program (Brainstim®) four times a week over a period of four weeks. After 16 training sessions all participants were evaluated again neuropsychologically.

Results

In both patient groups a significant increase in cognitive performance within the training procedure could be shown. This increase was expressed by an initial exponential function with a steep increase and an asymptotic slope. Pre-post-test-comparisons revealed significant improvement for shortterm and working memory on the neuropsychological outcomes. The program was well accepted by the patients.

Conclusion

This preliminary results show, that working memory might be trained in schizophrenia and thus it might interfere positively the cognitive und rehabilitative outcome.

Type
Psychotic disorders / Schizophrenia
Information
European Psychiatry , Volume 25 , Issue S1: 18th European Congress of Psychiatry. February 27, March 2, 2010 - Munich, Germany , 2010 , 25-E1107
Copyright
Copyright © European Psychiatric Association 2010
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