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A one year prevalence study of schizophrenia on Reunion Island

Published online by Cambridge University Press:  16 April 2020

M Jay ,
P Gorwood ,
J Feingold  and
M Leboyer
M Jay
Affiliation:
Saint Paul Psychiatric Hospital, Reunion Island, France
P Gorwood*
Affiliation:
Genetic Epidemiology, INSERM Unit 155, Université Paris VII, Paris, France Psychiatric Department, Louis Mourier Hospital, 178, rue des Renouillers, 92701Colombes, France
J Feingold
Affiliation:
Psychiatric Department, Louis Mourier Hospital, 178, rue des Renouillers, 92701Colombes, France
M Leboyer
Affiliation:
Psychiatric Department, Louis Mourier Hospital, 178, rue des Renouillers, 92701Colombes, France Psychiatric Department, Pitié-Salpêtrière Hospital, Paris, France
*
*Correspondence and reprints to the Colombes address.
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Summary

Review of geographical comparisons of the prevalence of schizophrenic disorders found a ten-fold range difference between geographical contiguous groups, with high and low prevalence pockets. We performed a 1-year prevalence study of schizophrenia in a limited area of Reunion Island in the Indian Ocean, and analysed the prevalence variability in contiguous regions of this area. We found one of the highest reported age-corrected (above 15 years) 1-year prevalence of schizophrenia (14.9 per thousand). Large discrepancies in the distribution of prevalence rates of schizophrenia were observed between the five towns analysed. Interestingly, when a higher prevalence was observed, it was highly correlated with an increase of the percentage of familial cases (r = 0.989, df = 3, P = 0.0014). Presence of founder effect often described in geographical isolates could explain the high prevalence rate and the heterogeneity between towns observed in our sample.

Keywords

schizophreniafamilial case prevalencefounder effect
Type
Original article
Information
European Psychiatry , Volume 12 , Issue 6 , 1997 , pp. 284 - 288
Copyright
Copyright © European Psychiatric Association 1997

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References

Andreassen, NCEndicott, JSpitzer, RLWinokur, GThe family history method using diagnostic criteria: reliability and vali-dity. Arch Gen Psychiatry 1977; 34: 1229–1235CrossRefGoogle Scholar
Beckmann, JSRichard, IHillaire, D, et al.A gene for limb-girdle muscular dystrophy maps to chromosome 15 by Lin-kage. CR Acad Sci Paris SER III–VIE 1991; 312: 141–148Google Scholar
Ben-Tovim, DCushnie, JThe prevalence of schizophrenia in a remote area of Bostwana. Br J Psychiatry 1986; 148: 576–580CrossRefGoogle Scholar
Book, JAWetterberg, LModrzewska, KSchizophrenia in a North Swedish geographical isolate 19001977: epidemio-logy, genetics and bio-chemestry. Clin Genet 1978; 14: 373–394Google Scholar
Egeland, JAHostertter, AMAmish, Study IAffective disor-ders among the Amish, 19761980. Am J Psychiatry 1983; 140: 56–61Google Scholar
Freeman, HAlpert, MPrevalence of schizophrenia in an urban population. Br J Psychiatry 1986; 149: 603–611CrossRefGoogle Scholar
Gorwood, PLeboyer, MJay, MPayan, CFeingold, JGender and age at onset in schizophrenia: impact of family history. Am J Psychiatry 1995; 152: 208–212Google ScholarPubMed
Gorwood, PLeboyer, MFallisard, BJay, MRouillon, FFeingold, JAnticipation in Schizophrenia: new lights on a controversial problem. Am J Psychiatry 1996; 153: 1173–1177Google ScholarPubMed
Gottesman, IIShields, Jeds. Schizophrenia, The Epigenetic Puzzle Cambridge: University Press, 1982 16–35Google Scholar
Jablensky, ASartorious, NCulture and schizophrenia. Psychol Med 1975; 5: 113–124CrossRefGoogle Scholar
Kato, MPsychiatric epidemiological surveys in JapanCaudill, WLin, TY eds. Mental Health Research in Asia and the Pacific Honolulu: East-West Center Press, 1969Google Scholar
Leboyer, MFilteau, MJJay, M, et al.Clinical subtypes and age at onset in schizophrenic siblings Psychiatry Res 1992; 41: 107–114CrossRefGoogle ScholarPubMed
Leff, JPsychiatry Around the Globe: A Transcultural View New York: Marcel Dekker, 1981Google Scholar
Murphy, HBMRaman, ACThe chronicity of schizophrenia in indigenous tropical peoples Br J Psychiatry 118 1971 489–497CrossRefGoogle ScholarPubMed
Torrey, FSchizophrenia and Civilization New York: Jason Aronson, 1980Google Scholar
Torrey, FPrevalence studies in Schizophrenia. Br J Psychiatry 1987; 150: 598–608CrossRefGoogle Scholar
Torrey, FMcGuire, MO'Hare, AWalsh, DSpellman, MEnde-mic psychosis in Western Ireland. Am J Psychiatry 1984; 141: 966–969Google ScholarPubMed
Vogel, FMotulsky, AGHuman Genetics. Problems and Approaches In: Vogel, FMotulsky, AG eds. Population genetics: consanguinity, genetic drift Berlin: Springer-Verlag, 1997 549–582Google Scholar
Wing, LWing, JHailey, ABahn, Asmith, HThe use of psy-chiatric services in three urban areas: an international case register study. Soc Psychiatry 1967; 2: 158–167CrossRefGoogle Scholar
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