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Neuroimaging studies of addiction: The need to incorporate real life data and profile heterogeneity

Published online by Cambridge University Press:  19 July 2023

G. Sescousse*
Affiliation:
INSERM, Lyon Neuroscience Research Centre, Vinatier hospital, Lyon, France

Abstract

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Abstract

Neuroimaging studies of addiction seek to understand the brain mechanisms that predispose to and support the maintenance of addictive behaviors. Traditional studies are case-control cross-sectional studies, i.e. they conceptualized individuals suffering from addiction as a homogenous group, and report lab-based experiments conducted at one particular point in time. In this talk, I will argue that a refined understanding of addictive behaviors requires the use of dimensional longitudinal studies. Using dimensions will reveal the existence of heterogenous profiles within diagnostic groups, and allow researchers to incorporate individual variability in their models. In turn, using longitudinal follow-up measures should allow researchers to determine whether brain-related abnormalities are predictive of symptoms in real-life. I will illustrate these points using a few example studies from the literature.

Disclosure of Interest

None Declared

Type
Abstract
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2023. Published by Cambridge University Press on behalf of the European Psychiatric Association
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