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Neurocognitive Functioning in Depressed Bipolar and Unipolar Patients: a Romanian Sample.

Published online by Cambridge University Press:  15 April 2020

F. Romosan ,
L.M. Ienciu ,
R.S. Romosan ,
V.R. Enatescu ,
I. Papava ,
L. Dehelean ,
A. Draghici  and
A. Voina
F. Romosan
Affiliation:
Neuroscience, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania
L.M. Ienciu
Affiliation:
Neuroscience, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania
R.S. Romosan
Affiliation:
Neuroscience, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania
V.R. Enatescu
Affiliation:
Neuroscience, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania
I. Papava
Affiliation:
Neuroscience, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania
L. Dehelean
Affiliation:
Neuroscience, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania
A. Draghici
Affiliation:
Adult Psychiatry, “Eduard Pamfil” Psychiatric Clinic, Timisoara, Romania
A. Voina
Affiliation:
Adult Psychiatry, “Eduard Pamfil” Psychiatric Clinic, Timisoara, Romania

Abstract

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Introduction

Neurocognitive deficit is present in both recurrent depressive disorder and bipolar disorder, both during the acute episode and euthymia.

Objectives

Identifying differences in neurocognitive functioning of depressive bipolar, depressive unipolar patients and a healthy control group.

Methods

This study was conducted in Timisoara, Romania, between 2009 and 2013 and consists of inpatients from the Timisoara Psychiatric Clinic, diagnosed with either bipolar disorder (n=65) or recurrent depressive disorder (n=87), according to ICD-10 criteria and a healthy control group (n=70). For assessing neurocognitive functioning we used the d2 Test of Attention and the Rey verbal memory test.

Results

We found statistically significant differences (p<0.001) between the patient groups and the control group regarding 'Total Number of Items Processed” (TN), 'Percentage of Errors” (E%) and 'Concentration Performance” (CP). We found no significant statistical differences between the two patient groups regarding the aforementioned parameters.

Conclusions

During depressive episodes, the severity of the neurocognitive deficit is similar in both bipolar and unipolar patients.

Type
Article: 0450
Information
European Psychiatry , Volume 30 , Issue S1: Abstracts of the 23rd European Congress of Psychiatry , March 2015 , pp. 1
Copyright
Copyright © European Psychiatric Association 2015
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