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Mindfulness-based cognitive therapy for major depressive disorder- a literature review

Published online by Cambridge University Press:  13 August 2021

D. Vasile ,
O. Vasiliu ,
A. Mangalagiu ,
B. Petrescu ,
C. Tudor  and
C. Candea
D. Vasile*
Affiliation:
Psychiatry, University Emergency Central Military Hospital Dr. Carol Davila, Bucharest, Romania
O. Vasiliu
Affiliation:
Psychiatry, University Emergency Central Military Hospital Dr. Carol Davila, Bucharest, Romania
A. Mangalagiu
Affiliation:
Psychiatry, University Emergency Central Military Hospital Dr. Carol Davila, Bucharest, Romania
B. Petrescu
Affiliation:
Psychiatry, University Emergency Central Military Hospital Dr. Carol Davila, Bucharest, Romania
C. Tudor
Affiliation:
Psychiatry, University Emergency Central Military Hospital Dr. Carol Davila, Bucharest, Romania
C. Candea
Affiliation:
Psychiatry, University Emergency Central Military Hospital Dr. Carol Davila, Bucharest, Romania
*
*Corresponding author.

Abstract

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Introduction

Mindfulness-based cognitive therapy (MBCT) is a third wave cognitive-behavioral therapy (CBT) that incorporates meditation exercises in the classical, structured intervention. Mindfulness has been associated with psychological well-being, and certain symptoms that occur in major depressive disorder (MDD), e.g. worries, ruminations, ideas of incapacity or self-devaluation, are considered potential targets for MBCT.

Objectives

To evaluate the current level of evidence for the MCBT efficacy in MDD.

Methods

A literature serach was performed in the main electronic databases, targeting clinical trials that evaluated in a randomized manner the efficacy of MCBT versus active comparators or placebo in patients with MDD.

Results

MBCT was efficient in a 10-week randomized controlled trial (RCT) versus standard treatment, and it decreased ruminations, increased patients quality of life, mindfulness abilities, and self-compassion. In another randomized, 8-week RCT, MBCT prevented relapses in MDD, with similar rates when compared to psychoeducation and standard treatment. A 26-month follow-up study evidenced the persistence of symptoms improvement detected after 12 months of the trial, when compared to active control group and treatment as usual. MCBT was compared to cognitive therapy in a randomized 8-week trial, and both treatments had similar efficacy in MDD relapse prevention.

Conclusions

MCBT may be an useful adjuvant to the current treatment in acute MDD, but it may also decrease the risk of relapse after psychotherapy termination.

Keywords

cognitive-behavioral therapymindfulnessmajor depressive disorderrelapse prevention
Type
Abstract
Information
European Psychiatry , Volume 64 , Special Issue S1: Abstracts of the 29th European Congress of Psychiatry , April 2021 , pp. S494
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of the European Psychiatric Association
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