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Manic episode following SARS-COV-2 Infection

Published online by Cambridge University Press:  01 September 2022

Z. Bencharfa*
Affiliation:
University Hospital Center Ibn Sina, Ar-razi Psychiatric Hospital, Salé, Morocco
Y. Amara
Affiliation:
University Hospital Center Ibn Sina, Ar-razi Psychiatric Hospital, Salé, Morocco
N. El Moussaoui
Affiliation:
University Hospital Center Ibn Sina, Ar-razi Psychiatric Hospital, Salé, Morocco
S. Belbachir
Affiliation:
University Hospital Center Ibn Sina, Ar-razi Psychiatric Hospital, Salé, Morocco
A. Ouanass
Affiliation:
University Hospital Center Ibn Sina, Ar-razi Psychiatric Hospital, Salé, Morocco
*
*Corresponding author.

Abstract

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Introduction

In December 2019, infection with the novel coronavirus (SARS-CoV-2) was first reported in the city of Wuhan, China. Although generally recognized for its often fatal respiratory problems, other neuropsychiatric complications are receiving increasing attention.

Objectives

We will try through a clinical case to explain the psychiatric disorders in the context of this infection, and to highlight the two main explanatory theories of psychiatric disorders, in relation with the SARS-Cov-2 infection.

Methods

We report here a case of SARS-CoV-2 infection in a 54-year-old female patient with no specific pathological history, including psychiatric, who presented a fever, anosmia, and asthenia in the absence of any respiratory signs. Her PCR came back positive and her chest CT scan was normal.The patient was treated with paracetamol with vitamin C,with good clinical improvement. She came 15 days later to the psychiatric emergency room with psychomotor excitement. The patient was motorically unstable, could not hold still, her mimicry was hypermobile, contact with her was familiar, she was logorrheic with flight of ideas,she verbalized multiple projects, her mood was euphoric and her sleep was disturbed. Her blood tests were unremarkable.

Results

The diagnosis of manic episode was retained, and the patient was put on Olanzapine 10 mg, sodium Valproate 1g and Lorazepam 2.5 mg in degression with good clinical improvement.

Conclusions

Although the data in the literature remain scarce concerning the impact of this virus on mental health, we will try through this clinical case to explain the psychiatric disorders in the context of this viral epidemic, due to stress and inflammation.

Disclosure

No significant relationships.

Type
Abstract
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of the European Psychiatric Association
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