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Lifetime and 12-month prevalence rates of sub-clinical psychosis symptoms in a community cohort of 50-year-old individuals

Published online by Cambridge University Press:  15 April 2020

W. Rössler ,
M.P. Hengartner ,
V. Ajdacic-Gross ,
H. Haker  and
J. Angst
W. Rössler*
Affiliation:
Department of General and Social Psychiatry, Psychiatric University Hospital, University of Zurich, Militärstrasse 8, 8004Zurich, Switzerland Collegium Helveticum, A Joint Research Institute between the University of Zurich and the Swiss Federal Institute of Technology, Zurich, Switzerland
M.P. Hengartner
Affiliation:
Department of General and Social Psychiatry, Psychiatric University Hospital, University of Zurich, Militärstrasse 8, 8004Zurich, Switzerland
V. Ajdacic-Gross
Affiliation:
Department of General and Social Psychiatry, Psychiatric University Hospital, University of Zurich, Militärstrasse 8, 8004Zurich, Switzerland
H. Haker
Affiliation:
Department of General and Social Psychiatry, Psychiatric University Hospital, University of Zurich, Militärstrasse 8, 8004Zurich, Switzerland
J. Angst
Affiliation:
Department of General and Social Psychiatry, Psychiatric University Hospital, University of Zurich, Militärstrasse 8, 8004Zurich, Switzerland
*
*Corresponding author. Department of General and Social Psychiatry, Psychiatric University Hospital, University of Zurich, Militärstrasse 8, 8004 Zurich, Switzerland. Tel.: +41 44 296 7400; fax: +41 44 296 7409. E-mail address:[email protected] (W. Rö ssler).
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Abstract

Background:

Estimation of prevalence rates of sub-clinical psychosis symptoms can vary considerably depending on the methodology used. Furthermore, discussions are ongoing how prevalence rates may differ across various syndromes.

Method:

We analyzed data from the prospective Zurich Study, assessing sub-clinical psychosis with a semi-structured clinical interview in a community cohort of 50 years old individuals. The higher-order factors of psychosis symptoms were analyzed with confirmatory factor analysis to validate the a priori specified symptom-structure. Further associations were examined with contingency tables and logistic regressions.

Results:

The confirmatory factor analysis was consistent with a structure with four higher-order syndromes. Those different syndromes were labeled “thought disorder” (lifetime prevalence = 10.6%), “ego disorder” (4.8%), “hallucination” (9.7%), and “schizotypy” (28.2%). A strong discrepancy was noted between the 12-month prevalence of any symptoms and those considered to be severe. Twelve-month prevalence rates of distressful syndromes ranged from 0.1% for hallucinations up to 6.6% for schizotypy. The most strongly interrelated syndromes were thought disorder and ego disorder (OR = 12.4).

Conclusion:

Our findings indicate a continuity of sub-clinical psychosis within the general population even though only a small proportion suffers from distressing symptoms. Our analyses showed that the syndromes identified here are similar to those found in full-blown schizophrenia, albeit in an attenuated form.

Keywords

EpidemiologyPrevalence ratesSub-clinical psychosisSchizotypyEgo disorderHallucination
Type
Original article
Information
European Psychiatry , Volume 28 , Issue 5 , June 2013 , pp. 302 - 307
Copyright
Copyright © European Psychiatric Association

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References

Angst, J, Dobler-Mikola, A, Binder, JThe Zurich study – a prospective epidemiological study of depressive, neurotic and psychosomatic syndromes. I. Problem, methodology. Eur Arch Psychiatry Neurol Sci 1984;234:13–20.CrossRefGoogle ScholarPubMed
Barrett, PStructural equation modelling: adjudging model fit. Pers Individ Dif 2007;42:815–824.CrossRefGoogle Scholar
Bebbington, PE, Nayani, TThe Psychosis Screening Questionnaire. Int J Meth Psych Res 1995;5:11–19.Google Scholar
Bentler, PM, Bonett, DGSignificance tests and goodness of fit in the analysis of covariance structure. Psychol Bull 1980;88:588–606.CrossRefGoogle Scholar
Carpenter, WT Jr.Criticism of the DSM-V risk syndrome: a rebuttal. Cogn Neuropsychiatry 2011;16:101–106.CrossRefGoogle ScholarPubMed
Chapman, LJ, Chapman, JP, Kwapil, TR, Eckblad, M, Zinser, MCPutatively psychosis-prone subjects 10 years later. J Abnorm Psychol 1994;103:171–183.CrossRefGoogle ScholarPubMed
Derogatis, LRSymptom Checklist 90, R-Version manual I: scoring, administration, and procedures for the SCL-90. Baltimore, MD: Johns Hopkins Press; 1977.Google Scholar
Drake, RJ, Dunn, G, Tarrier, N, Haddock, G, Haley, C, Lewis, SThe evolution of symptoms in the early course of non-affective psychosis. Schizophr Res 2003;63:171–179.CrossRefGoogle ScholarPubMed
Dunn, G, Pickles, A, Tansella, M, Vazquez-Barquero, JLTwo-phase epidemiological surveys in psychiatric research. Br J Psychiatry 1999;174:95–100.CrossRefGoogle ScholarPubMed
Eich, D, Ajdacic-Gross, V, Condrau, M, Huber, H, Gamma, A, Angst, J, et al.The Zurich Study: participation patterns and Symptom Checklist 90-R scores in six interviews, 1979–99. Acta Psychiatr Scand Suppl 2003;108:11–14.CrossRefGoogle Scholar
Finney, SJ, Distefano, CNon-normal and categorical data in structural equation modeling. Hancock, G.R.Mueller, R.O.Structural equation modeling: a second course. Greenwich, CT: Information Age Publishing: 2006. p. 269–314.Google Scholar
Hu, L, Bentler, PMCutoff criteria for fit indexes in covariance structure analysis: conventional criteria versus new alternatives. Struct Equation Model 1999;6:1–55.CrossRefGoogle Scholar
Johns, LC, Van Os, JThe continuity of psychotic experiences in the general population. Clin Psychol Rev 2001;21:1125–1141.CrossRefGoogle ScholarPubMed
Loch, AA, Wang, YP, Rossler, W, Tofoli, LF, Silveira, CM, Andrade, LHThe psychosis continuum in the general population: findings from the Sao Paulo Epidemiologic Catchment Area Study. Eur Arch Psychiatry Clin Neurosci 2011;261:519–527.CrossRefGoogle ScholarPubMed
Mcgrath, J, Saha, S, Chant, D, Welham, JSchizophrenia: a concise overview of incidence, prevalence, and mortality. Epidemiol Rev 2008;30:67–76.CrossRefGoogle Scholar
Merikangas, KR, Zhang, H, Avenevoli, S, Acharyya, S, Neuenschwander, M, Angst, JLongitudinal trajectories of depression and anxiety in a prospective community study: the Zurich Cohort Study. Arch Gen Psychiatry 2003;60:993–1000.Google Scholar
Muthén, LK, Muthén, BOMplus User's Guide. 6th ed. Los Angeles, CA: Muthén & Muthén; 1998-2010.Google Scholar
Raine, ASchizotypal personality: neurodevelopmental and psychosocial trajectories. Annu Rev Clin Psychol 2006;2:291–326.CrossRefGoogle ScholarPubMed
Raine, A, Benishay, D, The, S.P.Q.-B.A brief screening instrument for schizotypal personality disorder. J Pers Disord 1995;9:346–355.CrossRefGoogle Scholar
Rossler, W, Riecher-Rossler, A, Angst, J, Murray, R, Gamma, A, Eich, D, et al.Psychotic experiences in the general population: a twenty-year prospective community study. Schizophr Res 2007;92:1–14.CrossRefGoogle ScholarPubMed
Rössler, W, Hengartner, MP, Angst, J, Ajdacic-Gross, VLinking substance use with symptoms of sub-clinical psychosis in a community cohort over 30 years. Addiction 2012;107:1174–1184.CrossRefGoogle Scholar
Rossler, W, Hengartner, MP, Ajdacic-Gross, V, Haker, H, Gamma, A, Angst, JSub-clinical psychosis symptoms in young adults are risk factors for subsequent common mental disorders. Schizophr Res 2011;131:18–23.CrossRefGoogle ScholarPubMed
Saha, S, Chant, D, Welham, J, Mcgrath, JA systematic review of the prevalence of schizophrenia. PLoS Med 2005;2:e141.CrossRefGoogle ScholarPubMed
Schultze-Lutter, F, Schimmelmann, BG, Ruhrmann, SThe near Babylonian speech confusion in early detection of psychosis. Schizophr Bull 2011;37:653–655.CrossRefGoogle Scholar
Serretti, A, Olgiati, PDimensions of major psychoses: a confirmatory factor analysis of six competing models. Psychiatry Res 2004;127:101–110.CrossRefGoogle ScholarPubMed
Tandon, R, Keshavan, MS, Nasrallah, HASchizophrenia, “just the facts” what we know in 2008. 2. Epidemiology and etiology. Schizophr Res 2008;102:1–18.CrossRefGoogle ScholarPubMed
Van Os, J, Hanssen, M, Bijl, RV, Ravelli, AStrauss (1969) revisited: a psychosis continuum in the general population?. Schizophr Res 2000;45:11–20.CrossRefGoogle ScholarPubMed
Van Os, J, Linscott, RJ, Myin-Germeys, I, Delespaul, P, Krabbendam, LA systematic review and meta-analysis of the psychosis continuum: evidence for a psychosis proneness-persistence-impairment model of psychotic disorder. Psychol Med 2009;39:179–195.CrossRefGoogle ScholarPubMed
Yung, AR, Buckby, JA, Cosgrave, EM, Killackey, EJ, Baker, K, Cotton, SM, et al.Association between psychotic experiences and depression in a clinical sample over 6 months. Schizophr Res 2007;91:246–253.CrossRefGoogle Scholar
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