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Lifetime and 12-month prevalence rates of sub-clinical psychosis symptoms in a community cohort of 50-year-old individuals

Published online by Cambridge University Press:  15 April 2020

W. Rössler ,
M.P. Hengartner ,
V. Ajdacic-Gross ,
H. Haker  and
J. Angst
W. Rössler*
Affiliation:
Department of General and Social Psychiatry, Psychiatric University Hospital, University of Zurich, Militärstrasse 8, 8004Zurich, Switzerland Collegium Helveticum, A Joint Research Institute between the University of Zurich and the Swiss Federal Institute of Technology, Zurich, Switzerland
M.P. Hengartner
Affiliation:
Department of General and Social Psychiatry, Psychiatric University Hospital, University of Zurich, Militärstrasse 8, 8004Zurich, Switzerland
V. Ajdacic-Gross
Affiliation:
Department of General and Social Psychiatry, Psychiatric University Hospital, University of Zurich, Militärstrasse 8, 8004Zurich, Switzerland
H. Haker
Affiliation:
Department of General and Social Psychiatry, Psychiatric University Hospital, University of Zurich, Militärstrasse 8, 8004Zurich, Switzerland
J. Angst
Affiliation:
Department of General and Social Psychiatry, Psychiatric University Hospital, University of Zurich, Militärstrasse 8, 8004Zurich, Switzerland
*
*Corresponding author. Department of General and Social Psychiatry, Psychiatric University Hospital, University of Zurich, Militärstrasse 8, 8004 Zurich, Switzerland. Tel.: +41 44 296 7400; fax: +41 44 296 7409. E-mail address:[email protected] (W. Rö ssler).
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Abstract

Background:

Estimation of prevalence rates of sub-clinical psychosis symptoms can vary considerably depending on the methodology used. Furthermore, discussions are ongoing how prevalence rates may differ across various syndromes.

Method:

We analyzed data from the prospective Zurich Study, assessing sub-clinical psychosis with a semi-structured clinical interview in a community cohort of 50 years old individuals. The higher-order factors of psychosis symptoms were analyzed with confirmatory factor analysis to validate the a priori specified symptom-structure. Further associations were examined with contingency tables and logistic regressions.

Results:

The confirmatory factor analysis was consistent with a structure with four higher-order syndromes. Those different syndromes were labeled “thought disorder” (lifetime prevalence = 10.6%), “ego disorder” (4.8%), “hallucination” (9.7%), and “schizotypy” (28.2%). A strong discrepancy was noted between the 12-month prevalence of any symptoms and those considered to be severe. Twelve-month prevalence rates of distressful syndromes ranged from 0.1% for hallucinations up to 6.6% for schizotypy. The most strongly interrelated syndromes were thought disorder and ego disorder (OR = 12.4).

Conclusion:

Our findings indicate a continuity of sub-clinical psychosis within the general population even though only a small proportion suffers from distressing symptoms. Our analyses showed that the syndromes identified here are similar to those found in full-blown schizophrenia, albeit in an attenuated form.

Keywords

EpidemiologyPrevalence ratesSub-clinical psychosisSchizotypyEgo disorderHallucination
Type
Original article
Information
European Psychiatry , Volume 28 , Issue 5 , June 2013 , pp. 302 - 307
Copyright
Copyright © European Psychiatric Association

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