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Improving quality of life with nutritional supplementation in Schizophrenia: A literature review

Published online by Cambridge University Press:  01 September 2022

N. Hassan ,
N. Dumlao ,
K. Tran  and
A. Zamiri
N. Hassan
Affiliation:
Bronx Care Health System, Psychiatry, Bronx, United States of America
N. Dumlao*
Affiliation:
BronxCare Health System, Psychiatry, Bronx, United States of America
K. Tran
Affiliation:
Bronx Care Health System, Psychiatry, Bronx, United States of America
A. Zamiri
Affiliation:
BronxCare Health System, Psychiatry, New York, United States of America
*
*Corresponding author.

Abstract

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Introduction

Schizophrenia is a chronic and severe mental health disorder, affecting 20 million people worldwide. Diet is a social determinant of health and is among one of the modifiable prognostic factors for schizophrenics. Previous research in nutritional psychiatry has shown that a balanced and healthy diet in this patient population has the potential to improve cognition, decrease positive and negative symptoms of the disease, and improve the overall metabolic profile.1,3

Objectives

To understand the evidence on the role that nutritional supplements play in improving quality of life in Schizophrenia by improving cognitive symptoms and decrease mortality by decreasing chances of metabolic syndrome and CVD. Demonstrate how certain supplements can improve cognitive symptoms, and decrease positive and negative symptoms in schizophrenics

Methods

PubMed was used to search for articles within the past 10 years

Results

A total of 29 articles were initially generated, of which only 5 fit the search criteria. Each specific search produced more articles, and after carefully reading each, a total of 14 articles was determined to fit the criteria. All, but two articles included PANSS score assessment. The studies on vitamin D, cycloserine and omega 3’s produced conflicting

Conclusions

Supplementation of vitamin D, Konjac powder, D-cycloserine, sarcosine, and omega 3’s have the potential to improve symptomatology and enhance the quality of life of schizophrenics. D-serine and sodium benzoate have not been shown to be effective adjunctive treatments in schizophrenia. Due to a limited number of studies for each, more research is indicated to truly determine the public health significance.

Disclosure

No significant relationships.

Keywords

“schizophrenia” “nutrition” “supplements”“omega 3’s” “iron” “vitamin D” “vitamin C”“sarcosine”“D-serine” “sodium benzoate”
Type
Abstract
Information
European Psychiatry , Volume 65 , Special Issue S1: Abstracts of the 30th European Congress of Psychiatry , June 2022 , pp. S595
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of the European Psychiatric Association
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